Results 51 to 60 of about 58,419 (296)

Taurine and dopamine-related effects of ethanol. An experimental study in rodents [PDF]

, 2019
The reinforcing properties of alcohol (ethanol) are associated with activation of the mesolimbic dopamine system and the concomitant increase in dopamine in the nucleus accumbens (nAc).
Ulenius, Lisa
core   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

Taurine potentiates presynaptic NMDA receptors in hippocampal Schaffer collateral axons [PDF]

, 2006
We have previously shown that activation of presynaptic N-methyl-d-aspartate (NMDA) receptors (NMDAR) enhances the amplitude of the presynaptic fibre volley (FV) evoked in Schaffer collateral axons of rat hippocampal slices, by a mechanism independent of
Solís, Jose María, Suárez González, Luz María   +1 more
core   +1 more source

Dynamic changes of serum taurine and the association with gestational diabetes mellitus: A nested case-control study

Frontiers in Endocrinology, 2023
ObjectiveThere is a lack of risk factors that can effectively identify gestational diabetes mellitus (GDM) in early pregnancy. It is unclear whether serum taurine in the first trimester and dynamic changes have different characteristics in GDM women ...
Jia Wang, Yuanyuan Wang, Yuanyuan Wang, Wei Zheng, Xianxian Yuan, Cheng Liu, Ya Zhang, Ya Zhang, Wei Song, Xiaoxin Wang, Shengnan Liang, Xu Ma, Xu Ma, Guanghui Li   +13 more
doaj   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

Advanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen, Tao Wu, Zhen Shi, Ravi Kumar Verma, Linlin Sheng, Lei Tao, Mingming Yang, Yuchen Wang, Conggang Zhang, Hao Fan, Li Wu, Ligong Chen   +11 more
wiley   +1 more source

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

Advanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed, Denis Abu Sammour, Dirk C. Hoffmann, Philipp Sievers, Tobias Bausbacher, Melissa Hahn, Yasemin Ucal, Iris Mildenberger, Christiane A. Opitz, Stefan Schmidt, Michael Platten, Oliver Wasenmüller, Wolfgang Wick, Andreas von Deimling, Tobias Kessler, Carsten Hopf   +15 more
wiley   +1 more source

Dual origins of dairy cattle farming--evidence from a comprehensive survey of European Y-chromosomal variation [PDF]

, 2011
BACKGROUND: Diversity patterns of livestock species are informative to the history of agriculture and indicate uniqueness of breeds as relevant for conservation.
Ginja, Catarina, L. Pérez Pardal, Lucía Pérez-Pardal, Gama, Luis T., Daniel G Bradley, Ceiridwen J. Edwards, European Cattle Genetic Diversity Consortium, Ceiridwen J Edwards, Frauke Stock, Edwards, C.J., Lenstra, J.A., Isaäc J Nijman, Kantanen, J., Nijman, Isaäc J., Gautier 1, Mathieu, Juha Kantanen, Nijman, I.J., J. Kantanen, Johannes A Lenstra, Levéziel, Hubert, H., Pérez-Pardal, Lucía, Bradley, D.G., Levéziel, Hubert, F. Stock, Moazami-Goudarzi, Katayoun, Penedo, M. Cecilia T., Laloë, Denis, I. J. Nijman, M. C. T. Penedo, Ginja, C., Luis T. Gama, Tresset, A., M Cecilia T Penedo, null null, Luis T Gama, Isaäc J. Nijman, Moazami Goudarzi, Katayoun, D. G. Bradley, Daniel G. Bradley, Lenstra, Johannes A., Penedo, M.C., Johannes A. Lenstra, Catarina Ginja, Bradley, Daniel G., C. Ginja, Anne Tresset, Gama, L.T., J. A. Lenstra, Consortium, European Cattle Genetic Diversity, Oulmouden, Ahmad, Stock, Frauke, Perez-Pardal, L., Stock, F., A. Tresset, Dolf, Gaudenz, M. Cecilia T. Penedo, C. J. Edwards, L. T. Gama, Kantanen, Juha, G. Ceriotti, Edwards, Ceiridwen J., Tresset, Anne   +61 more
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Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source

Eye and taurine [PDF]

, 2014
Taurine is the most abundant amino acid in retina. Although unclear, its role is mainly related to its powerful antioxidant properties. The taurine concentrations in tissues are regulated by an exogenous intake through the nutrition.
HADJ-SAÏD, Wahiba, PICAUD, Serge, SAHEL, José-Alain, FROGER, Nicolas, ROSOLEN, Serge Georges, Hadj Saïd, Wahiba   +5 more
core   +1 more source

Taurine inhibits serum deprivation-induced osteoblast apoptosis via the taurine transporter/ERK signaling pathway

Brazilian Journal of Medical and Biological Research, 2011
Taurine has positive effects on bone metabolism. However, the effects of taurine on osteoblast apoptosis in vitro have not been reported. The aim of this study was to investigate the activity of taurine on apoptosis of mouse osteoblastic MC3T3-E1 cells ...
Lei-Yi Zhang, Yue-Ying Zhou, Fei Chen, Bing Wang, Jing Li, You-Wen Deng, Wei-Dong Liu, Zheng-Guang Wang, Ya-Wei Li, Dong-Zhe Li, Guo-Hua Lv, Bang-Liang Yin   +11 more
doaj   +1 more source