Results 71 to 80 of about 63,418 (298)

Eye and taurine [PDF]

, 2014
Taurine is the most abundant amino acid in retina. Although unclear, its role is mainly related to its powerful antioxidant properties. The taurine concentrations in tissues are regulated by an exogenous intake through the nutrition.
HADJ-SAÏD, Wahiba, PICAUD, Serge, SAHEL, José-Alain, FROGER, Nicolas, ROSOLEN, Serge Georges, Hadj Saïd, Wahiba   +5 more
core   +1 more source

Amino Acid Modified Polymer Mesh for Removal of the Heavy Metal Ions Pb2+, Hg2+, Cu2+, and Ni2+ From Aqueous Solutions

Chemie Ingenieur Technik, EarlyView.
Adsorbents for cations of copper, lead, mercury, and nickel are obtained via grafting polymer mesh with an acrylic acid copolymer and subsequent functionalization with an amino acid. A distinct influence of the type of amino acid on the adsorption occurs.
Claudia Adolfs, Jan Becker, Hoang‐My Pham‐Cong, Uwe Gohs, Axel Fischer, Marco Drache, Sabine Beuermann   +6 more
wiley   +1 more source

EkstraksiTaurin Alami dari Ikan Gindara (Lepidocybium flavobrunneum) sebagai Crude Taurine Powder

, 2014
Escolar (Lepidocybium flavobrunneum) is one species of deep sea fish distributed in tropical seas, one of which in Southern Ocean of Java and Sumatra. Escolar contain taurine compounds that can improve the body's physiological functions . The aim of this
Hayati, Sri
core  

Quantitative Systems Toxicology Model Predicts Obeticholic Acid‐Associated Liver Injury in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Clinical Pharmacology &Therapeutics, EarlyView.
Obeticholic acid (OCA), a synthetic analog of chenodeoxycholic acid, was approved in 2016 for the treatment of primary biliary cholangitis. Early clinical trials revealed elevated liver biomarkers in healthy subjects receiving supratherapeutic OCA doses (100–250 mg).
Abigail K. Mayo, James J. Beaudoin, Jeffrey L. Woodhead, Paul B. Watkins, Kim L. R. Brouwer   +4 more
wiley   +1 more source

Integrated assessment of rifampicin‐mediated induction of transporters and drug‐metabolizing enzymes in a long‐term human liver tissue chip system

Clinical Pharmacology &Therapeutics, EarlyView.
Rifampicin is a prototypical clinical inducer used in drug–drug interaction (DDI) studies. However, the clinical relevance and predictability of rifampicin‐mediated hepatic transporter induction remain poorly defined. Conventional hepatocyte culture models fail to capture clinically relevant regulation of transporters and drug‐metabolizing enzymes ...
Mattie E. Hartauer, Raeanne M. Lanphier, Shivam Ohri, Jessica Snyder, Jacqueline B. Tiley, John K. Fallon, Henry Ho, Murat Cirit, Shiny Amala Priya Rajan, Kim L. R. Brouwer   +9 more
wiley   +1 more source

High-dose taurine supplementation exacerbates alcohol-associated liver disease by inducing gut microbiota dysbiosis and bile acid dysregulation in mice

eGastroenterology
Background β-aminoethanesulfonic acid (taurine) is a conditionally essential amino acid that plays critical roles in bile acid (BA) conjugation, antioxidative defence and metabolic regulation. Previous studies showed that faecal taurine level was reduced
Lihua Zhang, Xing Gao, Xiang Zhang, Shaoyu Chen, Guihua Pan, Jingdan Pei, Lixian Chen, Rahul Pushparaj, Panpan Huang, Chunbao Sun, Md Manirujjaman, Chiung-Kuei Huang, Peng-Sheng Ting, Zhongbin Deng, Vatsalya Vatsalya, Craig J McClain, Wenke Feng   +16 more
doaj   +1 more source

Taurine increases hippocampal neurogenesis in aging mice

Stem Cell Research, 2015
Aging is associated with increased inflammation and reduced hippocampal neurogenesis, which may in turn contribute to cognitive impairment. Taurine is a free amino acid found in numerous diets, with anti-inflammatory properties.
Elias Gebara, Florian Udry, Sébastien Sultan, Nicolas Toni   +3 more
doaj   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

Clinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung, Nicholas Ieronimakis, Bothaina Mousa, Emily D. Sheikh, Sarah E. Ligon, Joshua W. Monson, Jennifer R. Damicis, Hillary J. Kinsman, Lydia E. Bettridge, Samuel L.M. Arnold, Edward J. Kelly, Jashvant D. Unadkat, Joanne Wang   +12 more
wiley   +1 more source

Metabolism of cysteine to taurine by rat hepatocytes.

, 1992
During the past two decades, many investigators have assumed that the major locus of regulation of cysteine catabolism is the partitioning of cysteinesulfinate between its decarboxylation and transamination pathways.
Stipanuk, Martha H., Banks, Mark F., Bagley, P.J.   +2 more
core   +1 more source

Taurine and tea polyphenols combination ameliorate nonalcoholic steatohepatitis in rats

BMC Complementary and Alternative Medicine, 2017
Background Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease, for which there is currently no safe and effective drug for therapy.
Wenhua Zhu, Siwen Chen, Ronggui Chen, Zhiqing Peng, Jun Wan, Benyan Wu   +5 more
doaj   +1 more source