Results 81 to 90 of about 46,807 (214)

Scientific Opinion on the safety and efficacy of taurine as a feed additive for all animal species

EFSA Journal, 2012
Taurine is a beta‐amino acid, not incorporated into proteins. Taurine is involved in a number of physiological processes. In cats, dietary taurine at requirement/allowance levels is safe with a margin of safety of between 4 and 20. The few data available
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

Separate mechanisms regulating accumbal taurine levels during baseline conditions and following ethanol exposure in the rat

Scientific Reports
Ethanol-induced dopamine release in the nucleus accumbens (nAc) is associated with reward and reinforcement, and for ethanol to elevate nAc dopamine levels, a simultaneous increase in endogenous taurine is required within the same brain region.
Karin Ademar, Lisa Ulenius, Anna Loftén, Bo Söderpalm, Louise Adermark, Mia Ericson   +5 more
doaj   +1 more source

From Salt‐Affected Marginal Land Resource to Remediation Agent: Halophyte‐Derived Biochar for Ameliorating Cd‐Contaminated Acidic Soil

Land Degradation &Development, EarlyView.
ABSTRACT Cadmium (Cd) contamination of acidic soils poses a significant threat to ecosystem stability and crop health. This study evaluated the potential of biochar derived from the halophyte Salicornia europaea (SBC), a salt‐tolerant plant that grows on saline‐alkali marginal land, to remediate Cd‐contaminated acidic soil.
Shaoqing Ge, Zhenyong Zhao, Ke Zhang, Changyan Tian   +3 more
wiley   +1 more source

Improving Fetal Single‐Voxel Magnetic Resonance Spectroscopy With Spectral Registration

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To evaluate whether spectral registration improves spectral quality and quantification reliability in in vivo single‐voxel fetal brain MRS: Methods Fourteen fetal PRESS datasets were acquired at 3 T at TE = 35 ms and TE = 135 ms. Raw data were processed with eddy‐current phase correction, coil combination, spectral registration, and ...
Andres Saucedo, Qinqin Yang, Ali Gholipour   +2 more
wiley   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

Whole‐Genome Sequencing and Resequencing of Hucho bleekeri Provides Insights into Genetic Mechanisms of Environmental Adaptation

Integrative Zoology, EarlyView.
A high‐quality chromosome‐level reference genome was constructed for Hucho bleekeri. Population structure and environmental adaptation of Hucho species were revealed by whole‐genome resequencing. ABSTRACT Salmonidae represents an important family in the study of genome evolution following genome duplication.
Yeyu Chen, Huanchao Yang, Zhao Liu, Xiaoyun Wu, Qinyao Wei, Yanling Chen, Jue Lin, Yi Yu, Quanyu Tu, Hua Li   +9 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Distinct Immunometabolic Profiles in Finnish and Russian Karelian Adolescents With Contrasting Allergy Risk

Allergy, EarlyView.
We compared Finnish and Russian Karelian adolescents with contrasting allergy burden using integrated proteomic, metabolomic, and transcriptomic profiling. Finnish adolescents showed a broader pro‐inflammatory PBMC secretory profile consistent with a low‐grade inflammatory phenotype.
Nanna Fyhrquist, Matilda Riskumäki, Piia Karisola, Anni Nieminen, Tiina Laatikainen, Hanna Sinkko, Laura Paalanen, Pekka Jousilahti, Erkki Vartiainen, Mika J. Mäkelä, Tari Haahtela, Harri Alenius   +11 more
wiley   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source