Results 101 to 110 of about 91,409 (249)

Taurine increases hippocampal neurogenesis in aging mice

open access: yesStem Cell Research, 2015
Aging is associated with increased inflammation and reduced hippocampal neurogenesis, which may in turn contribute to cognitive impairment. Taurine is a free amino acid found in numerous diets, with anti-inflammatory properties.
Elias Gebara   +3 more
doaj   +1 more source

Scans for signatures of selection in Russian cattle breed genomes reveal new candidate genes for environmental adaptation and acclimation [PDF]

open access: yes, 2018
Domestication and selective breeding has resulted in over 1000 extant cattle breeds. Many of these breeds do not excel in important traits but are adapted to local environments.
A Talenti   +108 more
core   +5 more sources

Effect of Water Suppression and Metabolite Cycling on Quantification of 1H MRS Spectra in the Human Brain at 3 Tesla

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose This study investigates the effect of VAPOR water suppression and metabolite cycling on metabolite quantification and macromolecules in proton magnetic resonance spectroscopy. Methods Single‐voxel semi‐LASER spectra (TR/TE = 3000/28 ms) and metabolite‐nulled spectra (macromolecules) were acquired in five healthy subjects in the ...
Dinesh K. Deelchand   +1 more
wiley   +1 more source

PCR Based Genotyping of Lulu Cattle of Nepal for A1, A2 Type Beta-caseins [PDF]

open access: yes, 2020
Lulu is an indigenous breed of cattle (Bos taurus) found in high altitude regions of western Nepal. Population of Lulu cattle has been declining due to introgression with other exotic breeds to increase milk productivity.
Budhathoki, N. (Nabina)   +7 more
core  

Genomic blueprints of sponge-prokaryote symbiosis are shared by low abundant and cultivatable Alphaproteobacteria [PDF]

open access: yes, 2019
Marine sponges are early-branching, filter-feeding metazoans that usually host complex microbiomes comprised of several, currently uncultivatable symbiotic lineages.
Cox, Cymon   +6 more
core   +4 more sources

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon   +5 more
wiley   +1 more source

Taurine reduces microglia activation in the brain of aged senescence-accelerated mice by increasing the level of TREM2

open access: yesScientific Reports
Alzheimer’s disease (AD), a chronic neurodegenerative disorder, is the leading cause of dementia. Over-activated microglia is related to amyloid-beta (Aβ) and phosphorylated tau (phospho-tau) accumulation in the AD brain.
Sharif Ahmed   +7 more
doaj   +1 more source

Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease [PDF]

open access: yes, 2014
Alzheimer's disease (AD) is a lethal progressive neurological disorder affecting the memory. Recently, US Food and Drug Administration mitigated the standard for drug approval, allowing symptomatic drugs that only improve cognitive deficits to be allowed
Cho, Soo Min   +10 more
core   +2 more sources

The Impact and Reliability of Tissue Segmentation on In Vivo Magnetic Resonance Spectroscopy Metabolite Quantification

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald   +12 more
wiley   +1 more source

Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. [PDF]

open access: yes, 2014
Human diets differ from those of non-human primates. Among few obvious differences, humans consume more meat than most non-human primates and regularly cook their food.
Blekhman, Ran   +5 more
core   +2 more sources

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