Results 201 to 210 of about 58,325 (234)

Paclitaxel (Taxol) in Breast Cancer

Hematology/Oncology Clinics of North America, 1994
Paclitaxel (Taxol) is a diterpine plant compound that was isolated initially from the bark of the western yew tree, Taxus brevifolia, but can now be produced by semisynthesis from a renewable source. Paclitaxel is the first new agent in the past decade to have confirmed single agent activity in breast cancer in excess of 50%.
Andrew Dorr, Michael A. Friedman, Susan G. Arbuck   +2 more
openaire   +3 more sources

Effects of taxol and taxol/hyperthermia treatments on the functional polarization of cytotoxic T lymphocytes

Cell Motility, 1993
AbstractImmunofluorescence staining, electron microscopy, and (51Cr) cytolytic release assays are used to investigate the effects of taxol and taxol/hyperthermia treatments on the microtubule organization and cytolytic activity of cytotoxic T lymphocytes (CTLs).
R. E. J. Mitchel, David L. Brown, J. D. Knox   +2 more
openaire   +3 more sources

Extravasation de paclitaxel (Taxol®)

La Revue de Médecine Interne, 1995
Paclitaxel is a new antimitotic derived from yew-tree, used for the treatment of ovarian and breast cancers. The local toxicity of paclitaxel is still poorly known. We report one of the first observations of accidental subcutaneous extravastion of paclitaxel.
A. de Gramont, B. Demuynck, C. Varette, S Cartier, Marcel Krulik, C. Louvet, Eric Raymond, M Mimoun, M Debray, C. Canuel, S Baux   +10 more
openaire   +3 more sources

Overview of Paclitaxel (TAXOL®)

Seminars in Oncology Nursing, 1993
The history of development of paclitaxel (TAXOL [Bristol-Myers Squibb Co., Princeton, NJ]) is a long story and serves as a model of perseverance for those involved in drug development. Notations of the use of products of the yew tree date back to the Celts, but it was in the 1950s to the 1960s that the National Cancer Institute (NCI) selected the ...
openaire   +3 more sources

Paclitaxel (Taxol)

New England Journal of Medicine, 1995
E K, Rowinsky, R C, Donehower
openaire   +2 more sources

Modified taxols. 2. Oxidation products of taxol

The Journal of Organic Chemistry, 1986
Neal F. Magri, David G. I. Kingston
openaire   +2 more sources

Taxol

2006
Spyros D. Georgatos, Panayiotis A. Theodoropoulos   +1 more
openaire   +1 more source

Asymmetric Total Synthesis of Taxol

Journal of the American Chemical Society, 2021
Ya-Jian Hu, Long Min, Chuang-Chuang Li
exaly  

Taxol's pedigree

The Lancet, 1995
openaire   +3 more sources

Modified Taxols, 7. A Method for the Separation of Taxol and Cephalomannine

Journal of Natural Products, 1992
Carol A. Ivey, A. A. Leslie Gunatilaka, David G. I. Kingston   +2 more
openaire   +2 more sources