Microscopic distribution of taxanes in freeze-fixed stems of Taxus cuspidata. [PDF]
Gong Q, Aoki D, Yoshida M, Fukushima K.
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Anticancer Effect of Mycotoxins From Penicillium aurantiogriseum: Exploration of Natural Product Potential. [PDF]
Bouhoudan A +3 more
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Rescuing and utilizing anticancer Nothapodytes species: Integrated studies from plant resources to natural medicines. [PDF]
Peng X, Cai X, Tang J, Ge J, Chen G.
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Multi-combination comparative transcriptome analysis response to MeJA and identifies genes putatively involved in oridonin biosynthesis in Isodon rubescens. [PDF]
Lian C +7 more
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Identification of Secondary Metabolites by Multi-Omics Methods. [PDF]
Fang X.
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Structure, evolution, and roles of MYB transcription factors proteins in secondary metabolite biosynthetic pathways and abiotic stresses responses in plants: a comprehensive review. [PDF]
Ma Z, Hu L, Zhong Y.
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Metabolic Engineering of Terpenoid Biosynthesis in Medicinal Plants: From Genomic Insights to Biotechnological Applications. [PDF]
Guo C, Xu S, Guo X.
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Metabolic engineering in microbes could be used to produce large amounts of valuable metabolites that are difficult to extract from their natural sources and too expensive or complex to produce by chemical synthesis. As a step towards the production of Taxol in the yeast Saccharomyces cerevisiae, we introduced heterologous genes encoding biosynthetic ...
Benedikt Engels, Stefan Jennewein
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Rewiring cellular metabolism for heterologous biosynthesis of Taxol
Natural Product Research, 2019Taxol is one of the anticancer drugs synthesized naturally in the evergreen Taxus brevifolia forest tree belonging to the yew family (Taxaceae) growing on the Pacific. There are reportedly evidence for treating ovarian, breast and lung cancers through this drug given its unique structural and functional features.
Amirhossein Nazhand +5 more
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