Results 201 to 210 of about 327,793 (259)

Production and bioprocessing of Taxol from Aspergillus niger, an endophyte of Encephalartos whitelockii, with a plausible biosynthetic stability: antiproliferative activity and cell cycle analysis. [PDF]

Microb Cell Fact
Gamal A, Fikry E, Tawfeek N, El-Shafae AM, El-Sayed ASA, El-Domiaty MM.   +5 more
europepmc   +1 more source

Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability

Almeida AC, Lacheheub C, Gasic I.
europepmc   +1 more source

The anti-cancer drug Taxol produced in endophytic fungi inhabiting Taxus media: Ecology, regulation and biosynthesis

, 2010
Sameh S. M. Soliman
openalex   +1 more source

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Rewiring cellular metabolism for heterologous biosynthesis of Taxol

Natural Product Research, 2020
Taxol is one of the anticancer drugs synthesized naturally in the evergreen Taxus brevifolia forest tree belonging to the yew family (Taxaceae) growing on the Pacific.
Amirhossein Nazhand, A. Durazzo, M. Lucarini, M. Mobilia, B. Omri, A. Santini   +5 more
semanticscholar   +4 more sources

Biosynthesis of Taxol

TAXOL®, 2021
H. Floss, U. Mocek
semanticscholar   +2 more sources

Synthetic biology for Taxol biosynthesis and sustainable production.

Trends in Biotechnology
Incomplete understanding of the biosynthetic pathway of the anticancer compound Taxol hinders its production by metabolic engineering. Recent reports by Jiang et al. and other groups now describe the missing steps in Taxol biosynthesis, notably including oxetane ring formation.
Linfeng Xie, Jiaoqi Gao, Yongjin J. Zhou
semanticscholar   +3 more sources

Oxetane Ring Formation in Taxol Biosynthesis Is Catalyzed by a Bifunctional Cytochrome P450 Enzyme.

Journal of the American Chemical Society, 2023
Taxol is a potent drug used in various cancer treatments. Its complex structure has prompted extensive research into its biosynthesis. However, certain critical steps, such as the formation of the oxetane ring, which is essential for its activity, have ...
Yong Zhao, Feiyan Liang, Yuman Xie, Yao-Tao Duan, Aggeliki Andeadelli, I. Pateraki, A. Makris, T. G. Pomorski, D. Staerk, S. Kampranis   +9 more
semanticscholar   +1 more source

Elucidation of the final steps in Taxol biosynthesis and its biotechnological production

Nature Synthesis
Feiyan Liang, Yuman Xie, Chi Zhang, Yong Zhao, M. S. Motawia, S. Kampranis   +5 more
semanticscholar   +2 more sources

Exogenous phenylalanine and ultrasound treatments improved Taxol biosynthesis in hazelnut cell culture

Plant Cell, Tissue and Organ Culture (PCTOC)
Maryam Jamali, Alireza Ghanbari, A. Estaji, E. Chamani, Amir Mohammad Naji, Sima Panahirad, Gholamreza Ghohari, I. Mirmazloum   +7 more
semanticscholar   +2 more sources

Taxol: biosynthesis, molecular genetics, and biotechnological applications

Applied Microbiology and Biotechnology, 2001
Over the past decade, Taxol and its closely related structural analogue Taxotere have emerged as very important antitumor agents. Their widespread use in the treatment of a variety of cancer types, their likely approval for the treatment of additional forms of cancer, and their use at earlier stages of intervention will lead to increased demand for ...
S, Jennewein, R, Croteau
openaire   +2 more sources