Results 101 to 110 of about 229,388 (307)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Anurans exhibit limited dispersion ability and have physiological and behavioural characteristics that narrow their relationships with both environmental and spatial predictors.
Diego Anderson Dalmolin +2 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The response of ecosystem structures and functions to eutrophication has been investigated worldwide. Yet, present knowledge on the effects of nutrient inputs on biotic diversity is unsystematic and mainly based on taxonomic composition.
Yanmin Cao +6 more
doaj +1 more source
The concept of β-diversity, defined as dissimilarity among communities, has been widely used to investigate biodiversity patterns and community assembly rules. However, in ecosystems with high taxonomic β-diversity, due to marked environmental gradients,
Sébastien Villéger +3 more
doaj +1 more source
Vertebrate taxonomic and functional hotspots in the Brazilian Atlantic Forest [PDF]
AMCS was supported by a Spanish Ramón y Cajal fellowship RYC2020-029407-I, funded by MICIN/AEI/10.13039/501100011033, and by “ESF Investing in your future”.
Hilário, Renato Richard +9 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The study describes an analysis of the impact of plantation forestry on the taxonomic diversity of plants in south-central Chile. In this biodiversity hotspot, plantations of non-native species like Pinus radiata D. Don, Eucalyptus globules Labill.
Braun, Andreas Christian +1 more
core +1 more source
1. While there has been increasing interest in how taxonomic diversity is changing over time, less is known about how long-term taxonomic changes may affect ecosystem functioning and resilience.
Beudert, Burkhard +4 more
core +1 more source

