Results 171 to 180 of about 183,225 (261)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Taxonomic diversity and abundance of enchytraeids (Annelida, Clitellata, Enchytraeida) in the Northern Palaearctic. 2. European Russia. [PDF]

Biodivers Data J
Saifutdinov RA, Degtyarev MI, Korobushkin DI, Artemieva SM, Byzov PS, Danilova MA, Ditts AA, Ermokhina KA, Garibian PG, Gorbunova AY, Guseva PA, Karlik EI, Kondratieva TY, Kupriyanov DA, Lebedev IM, Lebedeva NV, Nazarov PA, Neplyukhina AA, Noskova EA, Obolensky RR, Panchenkov AA, Popova AV, Pronina NA, Rüthi J, Schaepman-Strub G, Shakhab SV, Zaitsev AS, Zemlianskii VA, Zvychaynaya EY, Gongalsky KB.   +29 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Taxonomic Diversity of <i>Ranunculus</i> Section <i>Ranunculastrum</i> (Ranunculaceae) in Tajikistan, With an Identification Key and a New Species Based in Part on Molecular Phylogenetic Evidence. [PDF]

Ecol Evol
Erst AS, Boboev MT, Boboev KM, Baasanmunkh S, Sharples MT, Kuznetsov AA, Kulikovskiy MS, Kostikova VA, Maltseva SY, Erst TV, Skaptsov MV, Xiang K, Lian L, Choi HJ, Wang W.   +14 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Fine-Scale Variation in Soil Properties Promotes Local Taxonomic Diversity of Hybridizing Oak Species (Quercus spp.). [PDF]

Evol Appl
Zimmermann F, Reutimann O, Baltensweiler A, Walthert L, Olofsson JK, Rellstab C.   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Taxonomic diversity of microbial communities in the cold sulfur spring Bezymyanny (Pribaikalsky district, Republic of Buryatia). [PDF]

Vavilovskii Zhurnal Genet Selektsii
Banzaraktsaeva TG, Lavrentyeva EV, Dambaev VB, Ulzetueva ID, Khakhinov VV.   +4 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Taxonomic diversity of terrestrial vertebrates in west-central Mexico: Conservation from a multi-taxa perspective. [PDF]

PLoS One
Álvarez-Grzybowska E, Rosas-Espinoza VC, Peña-Joya KE, Santiago-Pérez AL, Íñiguez-Dávalos LI, Macías-Rodríguez MÁ, Rodríguez-Zaragoza FA.   +6 more
europepmc   +1 more source