Results 161 to 170 of about 229,388 (307)
The Fractal Dimension of Taxonomic Systems
, 1990 The hypothesis that biological diversity has a fractal geometry is tested through the examination of size-frequency distributions of taxa with different numbers of subtaxa. Data used derive from 44 checklists and catalogues of species concerning protists,
Bruno Burlando
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Diversity in small mammals from eastern Lake Turkana, Kenya
, 2010 Rodents and insectivores were surveyed, using live trapping, at seven sites on the eastern side of Lake Turkana, one of the remotest parts of Kenya, and at study areas of biological distinctiveness, such as Sibiloi National Park and the Mount Kulal ...
Fasola, M. +5 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Taxonomic Diversity of Prokaryotic Communities from Permafrost Active Layers of the Chilean Andes. [PDF]
MicroorganismsFaragó V, Borsodi AK, Nagy B.
europepmc +1 more source
A review of the taxonomic diversity, host-parasite interactions, and experimental research on chytrids that parasitize diatoms. [PDF]
Front Microbiol, 2023 Danz A, Quandt CA.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Elucidating the Functional and Taxonomic Diversity of Soil Microbial Communities From Three Commercial Soybean Farms in South Africa. [PDF]
Environ Microbiol RepNdhlovu K +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source