Results 141 to 150 of about 183,225 (261)

Beyond taxonomic diversity patterns - investigating how α and β components of macrophyte functional diversity respond to environmental gradients in lotic ecosystems of Greece. [PDF]

Front Plant Sci, 2023
Stefanidis K, Oikonomou A, Dimitrellos G, Tsoukalas D, Papastergiadou E.   +4 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Scale-Dependent Effects of Landscape Heterogeneity on Butterfly Functional and Taxonomic Diversity in Andean Urban Parks. [PDF]

Ecol Evol
Coral-Acosta N, Castaño JH, Jiménez DTR, Urbina-Cardona JN.   +3 more
europepmc   +1 more source

Organic and inorganic nutrients modulate taxonomic diversity and trophic strategies of small eukaryotes in oligotrophic oceans. [PDF]

FEMS Microbes, 2023
Villiot N, Maas AE, Poulton AJ, Blanco-Bercial L.   +3 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Taxonomic diversity and functional adaptations indicated by the rhizospheric soil microbiome derived from Turkish wheat fields. [PDF]

Biol Open
Güralp G, Acet SN, Al-Khodor J, Akkaya Ö, Şeker MG, Süzerer V, Çiftçi YÖ, Lucas SJ.   +7 more
europepmc   +1 more source

ITSoneWB: profiling global taxonomic diversity of eukaryotic communities on Galaxy. [PDF]

Bioinformatics, 2021
Tangaro MA, Defazio G, Fosso B, Licciulli VF, Grillo G, Donvito G, Lavezzo E, Baruzzo G, Pesole G, Santamaria M.   +9 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Taxonomic diversity of green plants (Viridiplantae) in the Caatinga Phytogeographic Domain: a study supported by environmental licensing. [PDF]

Biodivers Data J
Cotarelli VM, de Moura-Júnior EG, Lima LF, Fontana AP, Cruz LC, Rodrigues RG, Pifano DS.   +6 more
europepmc   +1 more source

Cryptic taxonomic diversity and high-latitude melanism in the glossiphoniid leech assemblage from the Eurasian Arctic. [PDF]

Sci Rep, 2022
Bolotov IN, Kondakov AV, Eliseeva TA, Aksenova OV, Babushkin ES, Bespalaya YV, Chertoprud ES, Dvoryankin GA, Gofarov MY, Klass AL, Konopleva ES, Kropotin AV, Lyubas AA, Makhrov AA, Palatov DM, Shevchenko AR, Sokolova SE, Spitsyn VM, Tomilova AA, Vikhrev IV, Zubrii NA, Vinarski MV.   +21 more
europepmc   +1 more source