Results 231 to 240 of about 2,026,427 (351)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Taxonomic Diversity and Interannual Variation of Fish in the Lagoon of Meiji Reef (Mischief Reef), South China Sea. [PDF]

Biology (Basel)
Gong Y, Zhang J, Chen Z, Cai Y, Yang Y.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Annotated Checklist of Poroid Hymenochaetoid Fungi in Central Asia: Taxonomic Diversity, Ecological Roles, and Potential Distribution Patterns. [PDF]

J Fungi (Basel)
Gafforov Y, Yarasheva M, Wang XW, Rašeta M, Rakhimova Y, Kyzmetova L, Bavlankulova K, Rapior S, Chen JJ, Langer E, Munnavarov B, Aslonov Z, Bakokhoja B, Zhou LW.   +13 more
europepmc   +1 more source

Correction: Taxonomic diversity of fungi deposited from the atmosphere. [PDF]

ISME J, 2020
Woo C, An C, Xu S, Yi SM, Yamamoto N.
europepmc   +1 more source

Proceedings of the International Symposium on Diversity and Taxonomy of Rhizobia, Wuhan, Hubei, China, 1994. Diversity and taxonomy of rhizobia.

, 1996
F.D. Li, T. A. Lie, W.X. Chen, J.C. Zho
openalex   +1 more source

Taxonomic Diversity, Functional Guilds, and Spatial Distribution of Endophytic Fungi in Healthy Spinach via Amplicon Sequencing [PDF]

Mahmuda Parveen, Sujit K. Ghosh
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Taxonomic Diversity and Functional Traits of Soil Bacterial Communities under Radioactive Contamination: A Review. [PDF]

Microorganisms
Belykh E, Maystrenko T, Velegzhaninov I, Tavleeva M, Rasova E, Rybak A.   +5 more
europepmc   +1 more source