Targeted control of supporting pathways in paclitaxel biosynthesis with CRISPR-guided methylation
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: Plant cell culture biomanufacturing is rapidly becoming an effective strategy for production of high-value plant natural products, such as therapeutic proteins and small molecules, vaccine adjuvants, and nutraceuticals.
Cassandra Brzycki Newton +2 more
doaj +1 more source
Quality evaluation of compounds in leaves of six Taxus species based on UPLC-MS/MS and chemometrics
Frontiers in Chemistry, 2023 Introduction:Taxus species are used as medicinal plants all over the world. The leaves of Taxus species are sustainable medicinal resources that are rich in taxoids and flavonoids.
Qingzhu Cai +13 more
doaj +1 more source
Transcriptome-wide identification and screening of WRKY factors involved in the regulation of taxol biosynthesis in Taxus chinensis. [PDF]
Sci Rep, 2018 WRKY, a plant-specific transcription factor family, plays important roles in pathogen defense, abiotic cues, phytohormone signaling, and regulation of plant secondary metabolism. However, little is known about the roles, functions, and mechanisms of WRKY
Zhang M +7 more
europepmc +2 more sources
Comparison of Chemical Composition and Antimicrobial Activities of the Essential Oil of Taxus Media and Taxus Chinensis Var. Mairei Leaves [PDF]
, 2011 The study was conceived to evaluate the difference in the chemical composition as well as the difference in the antimicrobial activities of the essential oils of Taxus media and Taxus chinensis var. mairei leaves.
Yong Chun Jin, Ke Yuan, Jing Zhang
core +1 more source
Three New Diterpenoids from Taxus Chinensis.
Chemical and Pharmaceutical Bulletin, 1993 The structures of taxchinins D and G and taxchin A have been determined by means of NMR spectroscopy and confirmed by X-ray analyses. The fomer two possess a rearranged taxane skeleton found in taxchinin A, while the latter has a taxane skeleton.
LI, Bo +4 more
openaire +3 more sources
Promotion Effects of Taxus chinensis var. mairei on Camptotheca acuminata Seedling Growth in Interplanting Mode [PDF]
, 2022 Wild Camptotheca acuminata Decne (C. acuminata) resources are becoming endangered and face poor growth. Preliminary investigation results found that the growth of C. acuminata in an artificial mixed forest of Taxus chinensis var.
Jiajing Guan +7 more
core +1 more source
Scientific Reports, 2020 Quantitative real-time PCR (qRT-PCR) is commonly used to measure gene expression to further explore gene function, while suitable reference genes must be stably expressed under different experimental conditions to obtain accurate and reproducible data ...
Kaikai Zhang +7 more
doaj +1 more source
Chemical components and functions of Taxus chinensis extract
Journal of King Saud University - Science, 2020 Abstract Taxus chinensis is a National level protected plant and has been for a long time, since it grows slowly and has low regenerative capacity. Consequently, no large base of raw material forest of taxus was formed. This study used Taxus chinensis as the study object, for analyzing the chemical composition of T.
Zhe Hu +5 more
openaire +1 more source
Metabolic Engineering of Taxane Biosynthesis in Taxus chinensis Plant Cell Culture [PDF]
, 2022 Ovarian, lung, and breast cancer impact millions globally and are a common cause of death in the United States. These cancerous diseases can be treated with the chemotherapeutic paclitaxel (Taxol), which is naturally produced by the Taxus plant genus ...
Harrison, Alexandra +3 more
core
Taxoids from Taxus chinensis [PDF]
, 2016 Two new taxoids, 13,15-epoxy-13-epi-taxayunnasin A (1) and taxchinin N (2), were isolated from the leaves and stems of Taxus chinensis. Compound 2 is the first taxoid to be reported with an α,β-unsaturated lactone at C-4, C-5, C-20, and C-2.
Yu Zhao (104852) +9 more
core +1 more source