Results 21 to 30 of about 238,637 (182)

Evaluating knowledge gain from TB leaflets for prison and homeless sector staff: the National Knowledge Service TB pilot

, 2008
Background: The National Knowledge Service (NKS) is a National Health Service initiative to make patient and public information available to patients and healthcare professionals.
Roy, Anjana, Abubakar, Ibrahim, Catchpole, Mike, Lipman, Marc, National Knowledge Service TB Project Board, Yates, Susan, Chapman, Ann, Monk, Philip   +7 more
core   +1 more source

TB STIGMA – MEASUREMENT GUIDANCE [PDF]

, 2018
TB is the most deadly infectious disease in the world, and stigma continues to play a significant role in worsening the epidemic. Stigma and discrimination not only stop people from seeking care but also make it more difficult for those on treatment to ...
Meershoek, Agnes, Ferris France, Nadine, Lewis, Dean, Mitchell, Ellen M. H, Nair, Tushar, Byrne, Elaine, Johnston, Lisa G., Malar, James, Daftary, Amrita, Citro, Brian, Mumba, Olive, Smyth, Caoimhe, Levy, Jens, van der Land, Julia, Leimane, Ieva, Engel, Nora, Ni Cheallaigh, Deirdre, Macintyre, Kate, van de Berg, Sarah, Craig, Gillian, Zwerling, Alice, Abdullaev, Timur, Conroy, Ronan R., Bhavaraju, Rajita, Macdonald, Stephen H-F   +24 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Assessing TB treatment outcomes in pregnant women living with HIV with drug-susceptible TB

Public Health Action
BACKGROUND: Limited data exist on TB treatment outcomes among pregnant women with TB. Physiological and immunological adaptations during pregnancy may affect the efficacy of TB treatment.
N. Hernandez-Morfin, S. Cohn, Z. Waja, R.E. Chaisson, N. Martinson, N. Salazar-Austin   +5 more
doaj   +1 more source

Missed opportunities for integrated testing of HIV and tuberculosis on the GeneXpert platform in Lesotho

African Journal of Laboratory Medicine, 2023
Background: Integrated testing, treatment and care are key strategies for addressing the dual burdens of tuberculosis and HIV. The GeneXpert instrument allows simultaneous HIV and tuberculosis testing, but its utilisation for integrated testing remains ...
Gamuchirai P. Gwaza, Monkoe Leqheka, Tsietso Mots’oane, Sabine Dittrich, Kekeletso Kao   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Scintillation and dosimetric properties of Tb-doped CaF2 translucent ceramics synthesized by the spark plasma sintering method

Journal of Asian Ceramic Societies, 2020
CaF2 translucent ceramics with different concentrations of Tb were synthesized by the spark plasma sintering (SPS) method, and their photoluminescence, scintillation and dosimetric properties were characterized.
Naoki Kawano, Daisuke Nakauchi, Fumiya Nakamura, Takayuki Yanagida   +3 more
doaj   +1 more source