Results 171 to 180 of about 192,488 (296)

circPDE4B downregulation triggers GEMIN5‑dependent translational stress response and autophagy to reduce MAPT pathology

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Circular RNAs (circRNAs) are emerging as key regulators of gene expression, synaptic plasticity, and neuronal function in Alzheimer's disease (AD). Here, we characterize the biological actions of circPDE4B, a highly expressed circRNA markedly reduced in AD. METHODS circPDE4B knockdown in neuronal progenitor cells was combined with
Sambhavi Puri, Sophie J. F. van der Spek, Mintao Lin, Zihan Wang, Jacob Porter, Junming Hu, Liyuan Hu, Alejandro N. Rondón‐Ortiz, Alexander Knyshov, Jenna L. Libera, Scott E. Counts, Debomoy K. Lahiri, Julia TCW, Andrew Emili, Xiaoling Zhang, Benjamin Wolozin   +15 more
wiley   +1 more source

Pregnancy after hematopoietic stem cell transplant: an international multicenter study. [PDF]

Blood Adv
Salooja N, Eikema DJ, Michonneau D, Tichelli A, Apperley JF, Akhtar S, Bourhis JH, Maertens J, Maghfoor I, Massarotti C, Collin M, Mielke S, Raiola A, Schaap N, Sedlacek P, Socie G, van der Werf S, Aljurf M, Kalwak K, Basak G, Peric Z, Penack O, Schoemans H.   +22 more
europepmc   +1 more source

Designing a communication strategy to promote Alzheimer's disease prevention: The CULTIVAMENTE campaign

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Awareness of Alzheimer's disease (AD) prevention remains limited in community settings, contributing to low adoption of evidence‐based recommendations. This study aimed to design a context‐tailored communication strategy for older adults and health‐care providers.
José M. Aravena, Hugo Castro, Ronald Poblete, Gillian Saavedra, Rocio Briceño, Waldo Torres, Mayerling Vecchi, Marilú Budinich, Patricio Fuentes, Cecilia Albala, Becca R. Levy   +10 more
wiley   +1 more source

Benzoate Drugs for Traumatic Brain Injury. [PDF]

J Clin Exp Immunol
Pahan S, Pahan K.
europepmc   +1 more source

Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths

Annals of Neurology, Volume 99, Issue 5, Page 1343-1353, May 2026.
Objective Though it is widely known that tau deposition affects brain structure, the precise localization of these effects is poorly understood, especially in relation to gyral and sulcal anatomy. We investigated whether tau pathology in Alzheimer's disease (AD) preferentially affects sulci, and particularly sulcal depths.
Samira A. Maboudian, Corrina S. Fonseca, Adam C. Martersteck, Yishu Chao, Yuheng Chen, Daniela Ushizima, Duygu Tosun, Lea T. Grinberg, Kevin S. Weiner, William J. Jagust, for the Alzheimer's Disease Neuroimaging Initiative   +10 more
wiley   +1 more source

Prevalence and predictors of hypotension on hospital arrival in traumatic brain injury: a prehospital HEMS cohort study. [PDF]

Sci Rep
Macaitė A, Scholl LS, Schwietring J, Rehberg S, Hoyer A, Thies KC.   +5 more
europepmc   +1 more source

GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background GATA binding protein 2 (GATA2) plays a crucial role in the differentiation, proliferation, and maintenance of hematopoietic stem cells (HSCs). GATA2 mutations have been identified in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but the impact of somatic GATA2 mutations on prognosis remains controversial ...
Xian Zhang, Bingjie Wang, Yujun Dong, Qingya Wang, Qian Wang, Jialin Zhu, Qingyun Wang, Na Han, Yuan Li   +8 more
wiley   +1 more source

Commentary: Post-traumatic benign paroxysmal positional vertigo: mechanisms, clinical phenotypes, and a structured clinical pathway for management. [PDF]

Front Neurol
Rust HM, Smith RM, Seemungal BM.
europepmc   +1 more source

Impact of Early Mobilization and Rehabilitation on Functional Outcomes Following Craniocerebral Gunshot Injuries

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Craniocerebral gunshot injury (CGI) is a severe form of traumatic brain injury associated with profound neurological, cognitive, and functional impairment, often requiring prolonged rehabilitation. We report the case of a 17‐year‐old boy with a penetrating CGI who presented with a Glasgow Coma Scale score of 3/15, intracranial hemorrhage, a ...
Md. Abdul Alim, Kazi Md Azman Hossain, Sabrina Tina, Mahmuda Akter Akhi, Azharul Islam   +4 more
wiley   +1 more source

Severe traumatic brain injury and long-term survival: a meta-analysis on life expectancy and mortality trends. [PDF]

Neurol Sci
Saviola D, Bruni S, Bonavita J, Zadra A, Ciavarella M, Cannavò G, De Tanti A.   +6 more
europepmc   +1 more source