Results 61 to 70 of about 74,126 (266)

Size-dependent behaviour of functionally graded sandwich microbeams based on the modified couple stress theory [PDF]

, 2015
Static bending, buckling and free vibration behaviours of size-dependent functionally graded (FG) sandwich microbeams are examined in this paper based on the modified couple stress theory and Timoshenko beam theory. To avoid the use of a shear correction
Thai, Huu-Tai, Vo, Thuc, Nguyen, Trung-Kien, Lee, Jaehong   +3 more
core   +1 more source

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

Regulatory Cooperation, Regional Trade Agreements, and World Trade Law: Conflict or Complementarity? [PDF]

, 2015
Today, the growing and aging population, and the rise of new global threats on human health puts an increasing demand on the healthcare system and calls for preventive actions.
Howse, Robert
core   +2 more sources

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

Cytoskeleton Alterations by Tributyltin (TBT) in Tunicate Phagocytes [PDF]

Ecotoxicology and Environmental Safety, 1998
The effects of tributyltin chloride (TBT) on cytoskeletal components, as possible cell targets of toxicity, were examined on cultured hemocytes of the colonial ascidian Botryllus schlosseri by means of indirect immunofluorescence. The immunotoxic effect of 10 microM TBT (sublethal concentration) consists of (1) inhibition of yeast phagocytosis, Ca2 ...
CIMA, FRANCESCA, BALLARIN, LORIANO, BRESSA G., BURIGHEL P.   +3 more
openaire   +3 more sources

Acceptability, feasibility and short-term outcomes of temperament based therapy with support (TBT-S): a novel 5-day treatment for eating disorders

Journal of Eating Disorders, 2023
Background Temperament Based Therapy with Support (TBT-S) aims to target the mechanisms underlying the aetiology and maintenance of eating disorders, and was developed as an adjunct to treatment as usual.
Kristin Stedal, Ingrid Funderud, Christina E. Wierenga, Stephanie Knatz-Peck, Laura Hill   +4 more
doaj   +1 more source

Regional Trade Agreements and International R&D Spillovers: Implications for Developing Countries

The Developing Economies, EarlyView.
ABSTRACT We provide new evidence on heterogeneous international research and development (R&D) spillovers from partners of regional trade agreements (RTAs) and non‐partners using a sample of 45 economies in the period 1995–2017. We construct separate R&D stocks for RTA partners and non‐partners and find that spillovers from RTA partners are stronger ...
Yukiko Sawada, Rinki Ito, Naoto Jinji
wiley   +1 more source

A microcalorimetric assay of tetrahymena thermophila for assessing tributyltin acute toxicity [PDF]

, 2008
The power-time curves of Tetrahymena thermophila exposed to tributyltin (TBT) were detected by microcalorimetry. Metabolic rate (r) decreased significantly while peak time (PT) increased with the enhancement of TBT level.
Chen, X. -J., Feng, W. -S., Miao, W., Peng, J. -H., Shen, Y. -F., Wan, C. -Y., Yu, Y. -H., Yu, YH, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China   +7 more
core   +1 more source

Improved prediction of symptomatic type 1 diabetes using a luciferase‐based assay to measure (pro)insulin autoantibodies

Diabetic Medicine, EarlyView.
Abstract Introduction Insulin autoantibodies (IAA) are key predictors of type 1 diabetes, particularly in young children. Micro‐radiobinding assays (RBA) are the gold standard for IAA measurement but have limitations. We assessed whether a luciferase immunoprecipitation system (LIPS) assay improved diabetes risk assessment.
Rebecca C. Wyatt, Cristina Brigatti, Sian L. Grace, Claire L. Williams, Ilaria Marzinotto, Ben T. Gillard, Elena Bazzigaluppi, Deborah Shoemark, Michela A.‐M. Chandler, Peter Achenbach, Lorenzo Piemonti, BOX Study Group, Isabel Wilson, Rachel Aitken, Ilana Kelland, Clare Megson, Chitrabhanu Ballav, Atanu Dutta, Michelle Russell‐Taylor, Rachel Besser, James Bursell, Shanthi Chandran, Sejal Patel, Anne Smith, Manohara Kenchaiah, Gomathi Margabanthu, Foteini Kavvoura, Chandan Yaliwal, AWAF, Rachel Aitken, Olivia Pearce, Sarah Stollery, Elinor Balch, Hanah Batholomew, Zhara Hashmi, Kathleen M. Gillespie, Vito Lampasona, Alistair J. K. Williams, Anna E. Long   +38 more
wiley   +1 more source