Results 81 to 90 of about 46,097 (206)

Mechano‐Chemical Coordination of Nanoparticle‐Based Artificial Antigen‐Presenting Cells Synergistically Tunes T Cell Activation and Expansion Phenotypes

Small, EarlyView.
Mechanically distinct nano artificial antigen‐presenting cells with independently controlled antibody density are used to reveal how physical and biochemical cues jointly regulate human T‐cell activation. Increasing stiffness and antibody density accelerates activation, enhances expansion, and promotes effector‐associated differentiation, whereas ...
Zichao Guo, Fei Hou, Yali Zhang, Zilin Ye, Yang Li, Supun Ranaweera, Yue Hui, Chun‐Xia Zhao   +7 more
wiley   +1 more source

Study on the preparation of aligned silver nanowire transparent conductive films by wind-assisted method and its structural and electrical properties

Results in Engineering
Silver nanowire transparent conductive films (AgNWs-TCF) exhibit excessively high junction resistance due to the presence of a large number of wire-to-wire junctions in their conductive networks.
Zhiqiang Hu, Yuehui Hu, Huiwen Liu, Yichuan Chen, Jianchun Wu, Hao Gao, Feng Yang, Shuai Zeng, Guangrong Song, Xiaopei Wang, Cong Wang, Jiashun Chen, Xiaohong Li   +12 more
doaj   +1 more source

A Novel Drug, CC-122, Inhibits Tumor Growth in Hepatocellular Carcinoma through Downregulation of an Oncogenic TCF-4 Isoform

Translational Oncology, 2019
Immunomodulatory drugs such as lenalidomide (LEN) have shown significant anti-tumor activity against hematologic malignancies and they may have similar actions on solid tumors as well.
Yoshito Tomimaru, Arihiro Aihara, Jack R. Wands, Costica Aloman, Miran Kim   +4 more
doaj   +1 more source

Economic and Land Use Impacts of Synthetic Dairy Production on a Dairy‐Intensive Economy: New Technology Moo‐ving In

Australian Journal of Agricultural and Resource Economics, EarlyView.
ABSTRACT Synthetic dairy products are promoted as an environmentally sustainable alternative to conventional dairy goods. This paper examines the potential economic, employment and land use impacts of large‐scale synthetic dairy production on Aotearoa New Zealand—the world's leading dairy exporter. Using a global, economy‐wide model, we simulate a case
Niven Winchester, Dominic White
wiley   +1 more source

Combination radiation and αPD-L1 enhance tumor control by stimulating CD8+ PD-1+ TCF-1+ T cells in the tumor-draining lymph node

Nature Communications
Combination radiotherapy (RT) and αPD-L1 therapy has potential to enhance local and distant (abscopal) tumor control, however, clinical results in humans have been variable.
Yang Shen, Erin Connolly, Meili Aiello, Chengjing Zhou, Prasanthi Chappa, Haorui Song, Patan Tippitak, Tarralyn Clark, Maria Cardenas, Nataliya Prokhnevska, Annapaola Mariniello, Isabelle De Bruyker, Meghana S. Pagadala, Vishal R. Dhere, Sarwish Rafiq, Aparna H. Kesarwala, Alexandre Orthwein, Susan N. Thomas, Shirley L. Zhang, Mohammad K. Khan, J. Brandon Dixon, Gregory B. Lesinski, Michael C. Lowe, Haydn Kissick, David S. Yu, Chrystal M. Paulos, Nicole C. Schmitt, Zachary S. Buchwald   +27 more
doaj   +1 more source

Incidence and risk factors for postpartum infections: A Norwegian cohort study, 2012–2020

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Nationwide registry data from 516 874 deliveries in Norway (2012–2020) show that postpartum infections are common and that endometritis/puerperal sepsis is increasing. Delivery‐related factors, especially emergency cesarean section, postpartum hemorrhage, and chorioamnionitis, show the strongest associations.
Kjerstine Røe, Ingvil Krarup Sørbye, Cecilie Fredvik Torkildsen, Anders Engeland, Hilde Marie Engjom, Roy Miodini Nilsen, Kari Klungsøyr   +6 more
wiley   +1 more source

Associated Injuries in Ankle Fractures Involving the Tillaux-Chaput Fragment in Adults

Foot & Ankle Orthopaedics
Category: Trauma; Ankle Introduction/Purpose: Tillaux-Chaput fractures (TCF) consist of fractures of the anterolateral distal tibia. They are considered a rare entity during adulthood and can occur in isolation or be associated with other injuries around
Jafet Massri-Pugin MD, Gabriel Matamoros MD, Sergio Morales MD, MSc, María Jesús Lira MSc, Jorge Filippi MD, MBA   +4 more
doaj   +1 more source

Learning Across the Divide: Understanding Knowledge Sharing Through Petrographic Analysis on Ceramics From the Rhine‐Meuse Delta During the Middle to Late Neolithic Transition (3400–2200 bce)

Archaeometry, EarlyView.
ABSTRACT Vlaardingen (VL) communities on the Dutch West coast (3400–2200 bce) are part of a unique, long‐term continuity in the European Neolithic. Despite large‐scale changes in European populations during the Neolithic, the genomic diversity and cultural practices of VL communities can be retraced to the Mesolithic.
Jisca de Bruin, Erik Kroon, Lasse van den Dikkenberg, Dennis Braekmans   +3 more
wiley   +1 more source

Comparison of X-ray and Computed Tomography Scan in the Diagnosis and Classification of Tillaux-Chaput Fractures in Adults

Foot & Ankle Orthopaedics
Category: Trauma; Ankle Introduction/Purpose: Anterolateral distal tibial fractures, also known as Tillaux-Chaput fractures (TCF), have slowly gained attention, considering the risk of chronic pain and osteoarthritis if not appropriately managed.
Jafet Massri-Pugin MD, Gabriel Matamoros MD, Sergio Morales MD, MSc, María Jesús Lira MSc, Pablo Mery MD, Gonzalo Díaz MD, Jorge Filippi MD, MBA   +6 more
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source