Results 181 to 190 of about 6,502,416 (289)

Pharmacokinetics, efficacy and safety of dupilumab administered with prefilled pen devices in patients aged <12 years with atopic dermatitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim For children with atopic dermatitis (AD), dupilumab is available as a prefilled syringe (PFS) from the age of 6 months and as a prefilled pen (PFP) for patients aged ≥2 years, in 200‐ and 300‐mg devices. This substudy of an ongoing open‐label extension study evaluated the pharmacokinetics, efficacy and safety of switching from a dupilumab PFS ...
Amy S. Paller   +9 more
wiley   +1 more source

A repertoire of middle leading practices: A large‐scale investigation of middle leadership in schools

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This article presents findings from an Australian study investigating the practices of middle leaders responsible for facilitating school development. Despite middle leaders being increasingly recognised as essential in the development of teaching and learning in schools, middle leadership remains under‐researched and comparatively overlooked ...
Peter Grootenboer   +3 more
wiley   +1 more source

Comparative Analysis of Bioreactor Design and Scale‐Up for Cultivated Meat Using Monte Carlo‐Based Timescale Modeling

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Cultivated meat offers a sustainable alternative to conventional livestock production but faces significant scale‐up challenges, particularly in bioreactor design for mammalian cell suspension cultures. This study presents a comparative analysis of stirred tank reactors (STR), bubble columns (BC), and airlift reactors (ALR) to assess their ...
Pieter Jan Theodoor Brorens   +2 more
wiley   +1 more source

Metabolic characteristics and chemical basis of matcha from cultivars with different leaf colors. [PDF]

open access: yesFront Nutr
Ding S   +10 more
europepmc   +1 more source

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon   +3 more
wiley   +1 more source

Flavor characteristics of different grades of Baiyaqilan tea: An integrated analysis based on sensory evaluation and metabolomics. [PDF]

open access: yesFood Chem X
Zhang F   +13 more
europepmc   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

open access: yesBMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li   +6 more
wiley   +1 more source

Functional diversification of CsCAD14 orchestrates synergistic phenylpropanoid biosynthesis to defend gray blight disease in tea plants. [PDF]

open access: yesSci Adv
Xu L   +12 more
europepmc   +1 more source

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