SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
This research seeks to test the impact and correlation between financial technology and cyber marketing strategies and their five dimensions and to study how financial technology can affect cyber marketing strategies by improving efficiency and ...
Assistant teacher Anas Falah Hassan +1 more
doaj +1 more source
Multi User Decision Support System For Teachers Sertification With HTTPS [PDF]
Education quality is a key condition to realize the life of a developed nation, modern dan Prosperous. (Fasli Jalal 2008) Teacher quality greatly affect the effectiveness of learning (Suherman, 2007, Rink, 2002).
Edi, Setiawan
core
Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan +12 more
wiley +1 more source
Teachers' Perception of Student Coping With Emergency Remote Instruction During the COVID-19 Pandemic: The Relative Impact of Educator Demographics and Professional Adaptation and Adjustment [PDF]
Magdalena Jelińska +1 more
openalex +1 more source
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Symposium Introduction: Stepping Into Their Power: The Development Of A Teacher Leadership Stance [PDF]
This introduction to the symposium on Teacher Leadership describes how a group of teachers have developed a definition of teacher leadership as a stance.
Smulyan, Lisa, , \u2776
core +2 more sources
Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source
of Tyranny and Martyrdom in Two plays Murder in Cathedral and Walls of Fear
This research paper deals with two plays: Iraqi play (Walls of Fear) by Iraqi dramatist Kadhim Imarn Mousa) and the second one is Murder in Cathedral by American Dramatist T.S.Eliot.Both dramatists present the martyr character from ordinary people but ...
Assist. Teacher: Kawakib Talib
doaj +1 more source
Teacher development for formative assessment. [PDF]
This article reports on the teacher development that occurred during a two-year research project on the formative assessment practices of primary and secondary school teachers of science.
Bell, Beverley, Cowie, Bronwen
core +1 more source

