Results 41 to 50 of about 2,551,214 (328)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Changing times in England: the influence on geography teachers’ professional practice [PDF]

, 2012
School geography in England has been characterised as a pendulum swinging between policies that emphasise curriculum and pedagogy alternately. In this paper, I illustrate the influence of these shifts on geography teacher's professional practice, by ...
Alexander R., Ball S., Ball S. J., Banks F., Barnett R., Beijaard D., Brooks C., Chan E., Clare Brooks, Clark C. M., Davidson G., DfES, DfES, DfES, Fullan M., Furlong J., Goodson I., Grossman P. L., Gunter H., Hargreaves A., Harrison P., Hipkins R., Kelly A. V., Lambert D., Lambert D., Lambert D., Lambert D., Leaton Gray S., Marsden W. E., Marsden W. E., McEwan H., Morgan J., Morley L., Morrish M., Ofsted, Rawling E., Rawling E., Roberts M., Roberts M., Roberts M., Sachs J., Scott D., Segall A., Shulman L., Simon B., Wagner T., Whitty G., Young M. F.D.   +47 more
core   +2 more sources

Implementation of environment-based learning model at the elementary education level: a systematic literature review

Jurnal Ilmiah Pendidikan Dasar
Literature reviews on the implementation of environmental-based learning models at the elementary education level are still very limited. This study uses a systematic literature review method on the implementation of environmental-based learning models ...
Suhartono Suhartono, Moh Salimi, Ratna Hidayah, Muna Fauziah, Jupriyanto Jupriyanto   +4 more
doaj   +1 more source

Jigsaw in teaching circulatory system: a learning activity on elementary science classroom

Biosfer, 2019
Jigsaw type cooperative learning is explored again to train students from an early age to become a small expert to reveal the effects it has on the cognitive achievement of elementary students.
Marleny Leasa, Yakub Lalyolik Sanabuky, John Rafafy Batlolona, Javier Julia Enriquez   +3 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Reflections on becoming a teacher and the challenges of teacher education [PDF]

, 2011
In this lecture, the context and conditions of becoming a teacher from the time of being selected into the programme, through the process of training and being retained to teach are discussed within the framework of Teacher Education in Nigeria.
Afe, John O.
core  

Investigating Educational Change: The Aga Khan University Institute For Educational Development Teacher Education For School Improvement Model [PDF]

, 2007
This article continues the analyses of the impact of an innovative teacher education programme aimed at school improvement in a developing country context (Khamis and Sammons 2004).
Khamis, Anil, Sammons, Pam
core   +3 more sources

Revitalizing Creativity: Enhancing Students' Creative Thinking through STEAM and Project-Based Learning in Human Respiration Studies

Scientiae Educatia: Jurnal Pendidikan Sains
One of the skills that students need to face global competition is the ability to think creatively. This study aims to determine the effect of applying the STEAM approach with the Project-Based Learning (PjBL) model on improving students' creative ...
Maidina Panduweni, Erna Suhartini, Rosita Putri Rahmi Haerani   +2 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Opportunities or new disadvantages? The long-term impact of curriculum modifications and accommodations on post-compulsory educational trajectories

Empirical Research in Vocational Education and Training
This study examines the long-term effects of two different integrative school measures in lower secondary education — reduced individual learning objectives and accommodations — on post-compulsory educational trajectories in Switzerland.
Sara Lustenberger, Caroline Sahli Lozano, Kathrin Brandenberg, Janine Hauser, Sergej Wüthrich   +4 more
doaj   +1 more source