IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui +12 more
wiley +1 more source
Psychological distress among early career university teachers: an ecological perspective. [PDF]
Duan M.
europepmc +1 more source
External pressure directly tunes the breathing distortion of the kagome lattice in Fe3Sn2, suppressing it near 15 GPa and reversing it at higher pressures. This structural modulation drives a cascade of Lifshitz transitions, reconstructs the Fermi surface, strengthens electronic correlations and carrier localization, and modifies ultrafast electron ...
Marcos Vinicius Gonçalves‐Faria +14 more
wiley +1 more source
Mathematics teaching outcome expectancy, self-handicapping, and mathematics teaching anxiety: a two-wave mediation study. [PDF]
Uras MC.
europepmc +1 more source
Discrete 2D Material Programming for 3D Shaping and Morphogenesis‐Inspired 4D Bioprinting
Cell‐compatible discrete 2D material programming enables 2‐to‐3D shape transformation and morphogenesis‐inspired 4D bioprinting. By patterning cell‐supportive microdomains within a responsive hydrogel, the approach programs in‐plane growth to encode target metrics.
Fereshteh Family +3 more
wiley +1 more source
The relationship between teachers' cognitive flexibility and perceptions of curriculum change: the mediating role of innovative behavior. [PDF]
Aytaç A.
europepmc +1 more source
A unified time‐series forecasting framework learns transferable battery capacity‐degradation patterns from 20 heterogeneous datasets spanning chemistries, formats, temperatures, and cycling conditions. A single model delivers competitive predictions on both known and previously unseen datasets, while physics‐guided representation learning improves ...
Joey Chan +8 more
wiley +1 more source
Early childhood education teachers' search for balance between children's developmental needs and the expectations of the curriculum. [PDF]
Kaya E.
europepmc +1 more source
The serial mediating effects of different types of academic stress on depression among high school students: a two-layer protective mechanism based on conservation of resources theory. [PDF]
Duan Y.
europepmc +1 more source
Catalysts of music performance anxiety: a qualitative exploration of undergraduate students through the person-environment-occupation framework. [PDF]
Cemali M, Akel BS.
europepmc +1 more source

