Results 31 to 40 of about 224,206 (263)

La enseñanza de las ciencias sociales en Colombia: lugar de las disciplinas y disputa por la hegemonía de un saber

open access: yesRevista de Estudios Sociales, 2015
This paper presents some episodes that illustrate how the teaching of history and the social sciences in Colombia has been a source of conflict among intellectuals, academics and the state.
Diego H. Arias Gómez
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Los jóvenes y la historia desde la perspectiva de profesores de brasil, Argentina y Uruguay

open access: yesClio y Asociados, 2010
This paper presents an analysis of the survey among secondary school teachers in Brazil, Argentina and Uruguay in 2008. This work is part of the research entitled “Youth and History.” The intention is to articulate the data obtained with the ...
María Paula González
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Hypermedia-Supported program and its effect on developing historical reasoning skills among first year secondary school students [PDF]

open access: yesInternational Journal of Instructional Technology and Educational Studies
This study investigated the effect of a hypermedia-supported program on developing historical reasoning skills among first-year secondary school students in Egypt.
kholoud ibrahem, Samia Fayed
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

German Question in 1945–1949: Research of the Problem in Anglo-American Historiography

open access: yesHistoria i Polityka, 2018
The article is devoted to the research of the main streams in Anglo-American historiography concerning German problem in 1945–1949. Two main directions in Anglo-American historical science are identified and characterized.
Iryna Kaviaka
doaj   +1 more source

The history laboratory: the student as the historian in search of the sources

open access: yesDidattica della storia, 2020
From the experiences of the research project "The history laboratory": the student as a historian looking for sources, promoted since 2018 by the National Institute for Documentation, Innovation and Educational Research (INDIRE), the essay focuses on the
Pamela Giorgi   +5 more
doaj   +1 more source

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