Results 51 to 60 of about 325,407 (313)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The history laboratory: the student as the historian in search of the sources

open access: yesDidattica della storia, 2020
From the experiences of the research project "The history laboratory": the student as a historian looking for sources, promoted since 2018 by the National Institute for Documentation, Innovation and Educational Research (INDIRE), the essay focuses on the
Pamela Giorgi   +5 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

German Question in 1945–1949: Research of the Problem in Anglo-American Historiography

open access: yesHistoria i Polityka, 2018
The article is devoted to the research of the main streams in Anglo-American historiography concerning German problem in 1945–1949. Two main directions in Anglo-American historical science are identified and characterized.
Iryna Kaviaka
doaj   +1 more source

Teaching Legal History – History of Legal Teaching: Introductory Remarks

open access: yesActa Universitatis Lodziensis Folia Iuridica, 2022
The article works as a set of introductory remarks that precede the collection of articles published under the title Teaching Legal History – History of Legal Teaching. In this article, the aims of the volume and its content are discussed.
Łukasz Jan Korporowicz
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

The Unessay as Native-Centered History and Pedagogy

open access: yes, 2022
The Unessay as Native-Centered History and Pedagogy explores how the unessay functions with an Introduction to Native History course that centers Native lived experiences and ...
Guiliano, Jennifer
core   +1 more source

ATATÜRK İLKELERİ ve İNKILÂP TARİHİ DERSİNİN UZAKTAN EĞİTİM ŞEKLİNDE VERİLMESİNİN ÖĞRENCİ GÖRÜŞLERİ AÇISINDAN DEĞERLENDİRİLMESİ

open access: yesTurkish History Education Journal, 2017
Bu araştırmanın amacı, Atatürk İlkeleri ve İnkılâp Tarihi dersini uzaktan eğitim olarak alan öğrencilerin bu dersin uzaktan eğitim şeklinde veriliyor olmasına ilişkin görüşlerini tespit etmektir. Araştırmada veri toplama aracı olarak kullanılan anketler,
Sezai ÖZTAŞ, Bülent KILIÇ
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Los jóvenes y la Historia en el Mercosur. Temporalidades y enseñanza de la Historia

open access: yesClio y Asociados, 2017
In this work we present a quantitative research that investigates the concepts of time more accepted among students. Data analyzed the Argentinian answers to the questionnaire of project ‘Youth and history in MERCOSUR’.
Juliano Mainardes Waiga
doaj   +1 more source

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