Results 171 to 180 of about 1,231,189 (358)

Serum Type I Interferon Score for Prediction of Clinically Meaningful Disease Progression in Limited Cutaneous Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess the value of serum type I interferon (IFN) score in predicting clinically meaningful progression in limited cutaneous systemic sclerosis (lcSSc) using a novel composite endpoint adopted from the MINIMISE clinical trial. Methods A retrospective, longitudinal lcSSc cohort was identified within a national, multicenter observational ...
Stefano Di Donato   +9 more
wiley   +1 more source

Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and TYK2 Inhibitors via IL10 Antagonism

open access: yesArthritis &Rheumatology, Accepted Article.
Background JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but TYK2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn's Disease, which highlights the complex role for JAK‐STAT signaling in different inflammatory processes. In this study, we investigated
Sami Giryes   +14 more
wiley   +1 more source

Asociación entre la presencia de estudiantes de medicina y los indicadores de calidad en pacientes obstétricas en un hospital universitario de Bogotá, Colombia: Estudio de corte transversal

open access: yesRevista Colombiana de Obstetricia y Ginecología, 2012
Objetivo: determinar si la presencia de estudiantes de medicina se asocia a diferencias en los indicadores de calidad de la atención y en la satisfacción de las pacientes obstétricas. Materiales y métodos: estudio de corte transversal.
Olga Lucía Pinto-Winkler   +1 more
doaj  

Machine Learning Analysis of Whole‐Blood Transcriptomics Data in Rheumatoid Arthritis Patients Treated with Adalimumab Identifies Predictive Biomarkers of Response

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Tumor necrosis factor inhibitors (TNFi) have significantly improved rheumatoid arthritis (RA) management, yet variability in patient response remains a substantial challenge, with approximately 40% of patients discontinuing TNFi due to non‐response or adverse effects. This study aimed to identify biomarkers predictive of adalimumab treatment
Chuan Fu Yap   +12 more
wiley   +1 more source

Medical students' initial experiences of the dissection room and interaction with body donors: A qualitative study of professional identity formation, educational benefits, and the experience of Pasifika students

open access: yesAnatomical Sciences Education, EarlyView.
Abstract The first experience of medical students in the dissecting room (DR) likely influences professional identity formation (PIF). Sparse data exist exploring how exposure to the DR and body donors without undertaking dissection influences PIF, or how culture may influence this experience.
Jacob Madgwick   +2 more
wiley   +1 more source

The history of anatomical engagement

open access: yesAnatomical Sciences Education, EarlyView.
Abstract The public's fascination with anatomy has evolved over time and progressed from avoidance of the tainted yet saintly corpse, to their fascination with cabinets of curiosities. The current narrative review explores public engagement (PE), from its potential origins as cave paintings, to the rise of the disciplinarity of anatomy.
Quenton Wessels, Adam M. Taylor
wiley   +1 more source

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