Results 51 to 60 of about 772,937 (315)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Designing an Attitude Scale for the Educational Technology in Sports Course for Second-Year Female Students at the Faculty of Sports Sciences [PDF]

open access: yesInternational Journal of Sports Science and Arts
Introduction & Research problem:The current study aims to design an attitude scale for the "Sport Education Technology" course for second-year female students at the Faculty of Sport Sciences.
Aya Abo alainan   +2 more
doaj   +1 more source

Teaching Visual Methods During COVID [PDF]

open access: yes, 2021
In March 2020, Suzanne Culshaw was due to come into one of Suzanne Albary's Research Methods seminars for MBA students to deliver a workshop on Visual Methods and using collage as data collection.
Albary, Suzanne, Culshaw, Suzanne
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

NCRM Bitesize Lessons for Teaching Social Science Research Methods 3: Learning from Learners [PDF]

open access: yes, 2023
This document is the third guide in the series NCRM Bitesize Lessons for Teaching Social Science Research Methods. It focuses on learning from learners.
Nind, Melanie
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

TEACHING METHODS

open access: yes, 2023
There is not any doubt that English has become a widely-spread language. Nowadays, English is utilized by as a minimum a thousand million humans across the world, both as a primary or as a 2nd language. It is impossible to forget about the want and the cost of techniques for coaching English as a foreign language or even as a 2nd language. Students are
Dushatova Shokhsanam Baxtiyor Qizi   +1 more
openaire   +3 more sources

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