Results 1 to 10 of about 68,976 (225)

Oldie but Goodie: Is Technetium-99m Still a Treasure Trove of Innovation for Medicine? A Patents Analysis (2000-2022). [PDF]

J Med Chem, 2023
Technetium-99m is the workhorse of diagnostic nuclear medicine. The aim of the work is to analyze the technetium-99m patents since 2000 to photograph its innovation. QUESTEL’s ORBIT Intelligence system was used for the collection of technetium inventions
Riondato M, Rigamonti D, Martini P, Cittanti C, Boschi A, Urso L, Uccelli L.   +6 more
europepmc   +2 more sources

Use of Technetium‐99m‐Pyrophosphate Single‐Photon Emission Computed Tomography/Computed Tomography in Monitoring Therapeutic Changes of Eplontersen in Patients With Hereditary Transthyretin Amyloid Cardiomyopathy [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Hereditary transthyretin amyloid cardiomyopathy (hATTR‐CM) is a progressive and fatal disease. Recent evidence indicates that bone scintigraphy may serve as a tool to monitor the effectiveness of hATTR‐CM treatment. The objective of this study
An‐Li Yu, Yi‐Chieh Chen, Cheng‐Hsuan Tsai, Yuan‐Kun Aden Wu, Mao‐Yuan Su, Chia‐Hung Chou, Chia‐Tung Shun, Hsueh‐Wen Hsueh, Jimmy Jyh‐Ming Juang, Ming‐Jen Lee, Ping‐Huei Tseng, Chia‐Hua Hsu, Sung‐Tsang Hsieh, Chi‐Lun Ko, Mei‐Fang Cheng, Chi‐Chao Chao, Yen‐Hung Lin   +16 more
doaj   +2 more sources

Indocyanine green fluorescence versus blue dye, technetium-99M, and the dual-marker combination of technetium-99M + blue dye for sentinel lymph node detection in early breast cancer-meta-analysis including consistency analysis.

Surgery, 2023
BACKGROUND Axillary sentinel lymph node biopsies are standard of care in patients with breast cancer and no clinically apparent metastases. Traditionally, technetium-99m, blue dye, or both have been used to identify sentinel lymph nodes.
Kevin P. White, D. Sinagra, F. Dip, R. Rosenthal, Edgar A. Mueller, E. Lo Menzo, Alberto Rancati   +6 more
semanticscholar   +1 more source

Exploratory Study of the Clinical Value of Near-Infrared Sentinel Lymph Node Mapping With Indocyanine Green in Vulvar Cancer Patients

Frontiers in Oncology, 2021
BackgroundThis study aimed to evaluate the clinical value of indocyanine green sentinel lymph node (SLN) mapping in patients with vulvar cancer. The conventional procedure of SLN mapping in vulvar cancer includes peritumoral injection of technetium-99m ...
Franziska Siegenthaler, Sara Imboden, Laura Knabben, Stefan Mohr, Andrea Papadia, Michael D. Mueller   +5 more
doaj   +1 more source

Technetium-99m-MIBI-SPECT for prostate cancer diagnosis

Український Журнал Нефрології та Діалізу, 2020
The gold standard method for prostate cancer diagnosis is a transrectal ultrasonography-guided prostate biopsy. The detection rate of prostate cancer using the biopsy is approximately 25-30%.
M. Kuru, Z. Talat, M. S. Sağer, Ç. Demirdağ   +3 more
doaj   +1 more source

Lymphoscintigraphy Using Tilmanocept Detects Multiple Sentinel Lymph Nodes in Melanoma Patients

Cancer Control, 2023
Background Technetium-99m-labeled Tilmanocept, a multivalent mannose, is readily internalized by the CD206 surface receptor on macrophages and dendritic cells which are abundantly present in lymph nodes.
Daniel M. Balkin MD, PhD, Gregory J. Tranah PhD, Frederick Wang MD, Cristina O’Donoghue MD, MPH, Emily A. Morell MD, Caitlin Porubsky DO, Mehdi Nosrati MS, Edith M. Vaquero BA, HanKyul Kim BA, Michael J. Carr MD, Jaime L. Montilla-Soler MD, Max C. Wu MD, Donald M. Torre CNMT, Mohammed Kashani-Sabet MD, Jonathan S. Zager MD, FACS, Stanley P. Leong MD, MS, FACS   +15 more
doaj   +1 more source

Physicochemical and Biological Study of ^99mTc and ⁶⁸Ga Radiolabelled Ciprofloxacin and Evaluation of [^99mTc]Tc-CIP as Potential Diagnostic Radiopharmaceutical for Diabetic Foot Syndrome Imaging

Tomography, 2021
This paper presents the application of ciprofloxacin as a biologically active molecule (vector) for delivering diagnostic radiopharmaceuticals to the sites of bacterial infection.
Przemysław Koźmiński, Weronika Gawęda, Magdalena Rzewuska, Agata Kopatys, Szymon Kujda, Marta K. Dudek, Paweł Krzysztof Halik, Leszek Królicki, Ewa Gniazdowska   +8 more
doaj   +1 more source

Technetium-99m in production and use [PDF]

Nuclear Technology and Radiation Protection, 2009
Several types of generators have been developed for the production of 99mTc. Due to its excellent performances, the chromatographic type, based on the fission-produced 99Mo sorbed in alumina, is predominant.
Vučina Jurij, Nikolić Nadežda, Petrović Đokica   +2 more
doaj   +1 more source

Diagnosing Transthyretin Cardiac Amyloidosis by Technetium 99m Pyrophosphate: A Test in Evolution.

JACC Cardiovascular Imaging, 2020
OBJECTIVES This study aimed to characterize trends in technetium Tc 99m pyrophosphate (99mTc-PYP) scanning for amyloid transthyretin cardiac amyloidosis (ATTR-CA) diagnosis, to determine whether patients underwent appropriate assessment with monoclonal ...
T. Poterucha, P. Elias, S. Bokhari, A. Einstein, A. Deluca, Mona P. Kinkhabwala, L. Johnson, K. Flaherty, S. Saith, J. Griffin, A. Perotte, M. Maurer   +11 more
semanticscholar   +1 more source

Technetium Tc 99m tilmanocept fails to detect sentinel lymph nodes in endometrial cancer

Gynecologic Oncology Reports, 2022
Background: Technetium Tc 99m tilmanocept is a synthetic radiotracer specifically designed for sentinel lymph node (SLN) mapping that has been FDA-approved in breast cancer, melanoma, and head and neck cancer.
Ravali A. Reddy, Ashley S. Moon, Stephanie Chow, Lucas Heilbroner, Brooke Howitt, Elisabeth Diver, Oliver Dorigo, Babak Litkouhi, Malte Renz, Amer Karam   +9 more
doaj   +1 more source