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Technetium-99m radiopharmaceuticals
1995Technetium is a group VIIB transition element which has seven electrons beyond the noble gas electronic configuration. The other members of the group are manganese (Mn) and rhenium (Re); together they form a triad (Mn, Tc, Re). All three elements easily lose the seven electrons to yield the +7 oxidation state of permetallate anions (MnO− 4, TcO− 4, ReO−
Azuwuike Owunwanne +2 more
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Reproducibility of technetium-99m ethylenedicysteine clearance
European Journal of Nuclear Medicine and Molecular Imaging, 1999It has been shown that technetium-99m ethylenedicysteine ((99m)Tc-EC) clearance displays a strong correlation with orthoiodohippurate clearance and that it is possible to estimate effective renal plasma flow from (99m)Tc-EC clearance. However, in routine practice, when monitoring renal function of patients by clearance determinations it is imperative ...
L, Kabasakal +4 more
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Organ Visualisation with Technetium 99m Preparations
The British Journal of Radiology, 1967Abstract Selected examples are presented in this paper to illustrate the potentialities of the use of some of the 99mTc compounds for organ visualisation. Although no attempt has been made at clinical evaluation, the additional information which can be gained by this means is both useful and impressive to those familiar with the technique.
I, Kazem, P, Gelinsky, P, Schenck
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Chemical & Engineering News Archive, 2012
The key medical isotope technetium-99m can be produced directly in hospital cyclotrons, rather than by extracting the isotope from material made in nuclear reactors, a team of Canadian researchers ...
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The key medical isotope technetium-99m can be produced directly in hospital cyclotrons, rather than by extracting the isotope from material made in nuclear reactors, a team of Canadian researchers ...
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Uptake of technetium 99m MDP by hepatoblastoma
European Journal of Nuclear Medicine, 1987Focal uptake of 99mTc-MDP was seen in a case of hepatoblastoma. The focal uptake corresponded to an area of calcification on CT, which was shown histologically to consist of osteoid with mineralization. The mechanism of uptake by the tumor in this case is likely to be the same as for skeletal uptake.
D A, Cory, A R, Siddiqui, M D, Cohen
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Technetium-99m Radiopharmaceuticals
2010The name technetium was derived by the scientist Mendeleyev from the Greek word technetos, meaning “artificial.” Technetium-99m was discovered in 1937 by Perrier and Segre in a sample of naturally occurring 98Mo irradiated by neutrons and deuterons. The first generator as a source for Tc-99m was introduced in 1957 at the Brookhaven National laboratory,
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Technetium-99m Pharmaceuticals
2007I.- Drug Safety.- Technetium in Medicine.- Stannous Chloride in the Preparation of 99mTc Pharmaceuticals.- Quality Assurance of Radiopharmaceuticals.- Performance and Quality Control of the 99Mo/99mTc Generator.- Preparation of Technetium 99mTc Pharmaceuticals.- Lyophilization Technique for Preparing Radiopharmaceutical Kits.- Cellular Labeling with ...
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Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998
Scintigraphic techniques are routinely used for the evaluation of the extent and severity of inflammatory bowel disease. Currently, the radiopharmaceutical of choice is 99mTc-hexamethyl propyleneamine oxime (HMPAO)-leukocytes. We studied the imaging potential of two recently developed 99mTc-labeled agents, polyethylene glycol (PEG)-coated liposomes and
Dams, E.T.M. +7 more
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Scintigraphic techniques are routinely used for the evaluation of the extent and severity of inflammatory bowel disease. Currently, the radiopharmaceutical of choice is 99mTc-hexamethyl propyleneamine oxime (HMPAO)-leukocytes. We studied the imaging potential of two recently developed 99mTc-labeled agents, polyethylene glycol (PEG)-coated liposomes and
Dams, E.T.M. +7 more
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Clinical experience with technetium 99m teboroxime
Seminars in Nuclear Medicine, 1991Technetium 99m teboroxime is a boronic acid adduct of technetium dioxime complex, a neutral lipophilic technetium-containing myocardial perfusion imaging agent with high myocardial extraction, rapid myocardial washout, and entero-hepatic excretion. Early "redistribution" occurs, and, based on preliminary animal data, appears to be due to differential ...
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Scintimammography with technetium-99m tetrofosmin
European Journal of Nuclear Medicine, 1996MANSI, Luigi, RAMBALDI PF
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