Results 11 to 20 of about 36,691 (260)

Successful application of technetium-99m-labeled octreotide acetate scintigraphy in the detection of ectopic adrenocorticotropin-producing bronchial carcinoid lung tumor: a case report [PDF]

open access: yesJournal of Medical Case Reports, 2010
Introduction The diagnostic efficacy of somatostatin receptor scintigraphy labeling with 111 indium in the localization of tumors has been assessed in a limited number of patients with contradictory outcomes.
Fallahi Babak   +7 more
doaj   +2 more sources

Preparation and Bioevaluation of Novel 99mTc-Labeled Complexes with a 2-Nitroimidazole HYNIC Derivative for Imaging Tumor Hypoxia

open access: yesPharmaceuticals, 2021
To develop novel 99mTc-labeled single-photon emission computed tomography (SPECT) radiotracers for imaging hypoxia, a novel HYNICNM ligand (6-hydrazinonicotinamide (HYNIC) 2-nitroimidazole derivative) was designed and synthesized.
Qing Ruan   +4 more
doaj   +1 more source

Positron emission tomography detects evidence of viability in rest technetium-99m sestamibi defects [PDF]

open access: yes, 1994
Objectives. The purpose of this study was to determine the relative value of single-photon emission computed tomographic (SPECT) imaging at rest using technetium-99m methoxyisobutyl isonitrile (technetium-99m sestamibi) with positron emission tomography ...
Allman, Kevin C.   +7 more
core   +1 more source

Comparison of Post-injection Site Pain Between Technetium Sulfur Colloid and Technetium Tilmanocept in Breast Cancer Patients Undergoing Sentinel Lymph Node Biopsy. [PDF]

open access: yes, 2015
BackgroundNo prior studies have examined injection pain associated with Technetium-99m Tilmanocept (TcTM).MethodsThis was a randomized, double-blinded study comparing postinjection site pain between filtered Technetium Sulfur Colloid (fTcSC) and TcTM in ...
Baker, Jennifer L   +6 more
core   +1 more source

A Picture of Modern Tc-99m Radiopharmaceuticals: Production, Chemistry, and Applications in Molecular Imaging

open access: yesApplied Sciences, 2019
Even today, techentium-99m represents the radionuclide of choice for diagnostic radio-imaging applications. Its peculiar physical and chemical properties make it particularly suitable for medical imaging.
Alessandra Boschi   +2 more
doaj   +1 more source

Synthesis and Evaluation of 99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

open access: yesPharmaceuticals, 2023
When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms.
Qing Ruan   +6 more
doaj   +1 more source

Technetium Complexes and Radiopharmaceuticals with Scorpionate Ligands

open access: yesMolecules, 2018
Scorpionate ligands have played a crucial role in the development of technetium chemistry and, recently, they have also fueled important advancements in the discovery of novel diagnostic imaging agents based on the γ-emitting radionuclide ...
Petra Martini   +5 more
doaj   +1 more source

Effect of an extract of Centella asiatica on the biodistribution of sodium pertechnetate (Na99mTcO4) and on the fixation of radioactivity on blood constituents [PDF]

open access: yes, 2008
This study evaluates the effects of an acute treatment with a Centella asiatica (CA) extract on the biodistribution of the radiopharmaceutical Na99mTcO4 and on the fixation of technetium-99m on blood constituents. Wistar rats were treated with CA extract
Adenilson de Souza da Fonseca   +22 more
core   +4 more sources

False‑positive technetium‑99m methylene diphosphonate bone scan activity in the orbit in a patient with a history of breast carcinoma [PDF]

open access: yes, 2018
Metastasis of breast carcinoma to the orbit is an uncommon entity and carries a poor prognosis. This case report presents false-positive technetium-99m methylene diphosphonate activity in the right orbit of a patient with a history of a primary breast ...
Bonnet, Sarah E., Palko, Joel R.
core   +2 more sources

The optimization method for synthesis of technetium-99m-luteolin as radiotracer in the development of cancer drugs from flavonoid

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2020
The aim of this study is to find the optimum conditions of labeling luteolin flavonoid compounds with technetium-99m (99mTc) to meet the purity requirements stated in the United States Pharmacopeia. This compound is expected to be a potential radiotracer
Danni Ramdhani   +2 more
doaj   +1 more source

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