Results 161 to 170 of about 24,612 (260)
Tomitaro ISHIMORI +2 more
openaire +2 more sources
A Self‐Organized Liquid Reaction Container for Cellular Memory
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee +4 more
wiley +1 more source
Detection of Metastatic Parathyroid Carcinoma with <sup>99m</sup>Tc-Sestamibi SPECT/CT Imaging. [PDF]
Jain V, Saini VK, Narayan ML.
europepmc +1 more source
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu +11 more
wiley +1 more source
What are the Safest and Easiest Extra-Cardiac Biopsy Sites for the Diagnosis of Wild-Type Transthyretin Cardiac Amyloidosis? Confirmation of the Diagnosis by Biopsy of the Pectoralis Muscle During Pacemaker Insertion. [PDF]
Takahashi K +6 more
europepmc +1 more source
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen +12 more
wiley +1 more source
Lingual Thyroid in Chronic Hypothyroidism. [PDF]
Onwudiwe O, Oputa-Onwusa O, Rajamani K.
europepmc +1 more source
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source

