Results 91 to 100 of about 3,891,508 (332)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Report Writing (or a few useful things about writing) [PDF]

open access: yes, 2009
Lecture Slides on the topic of report writing which incorporate a few in class activities.
White, Su
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Staffing and Managing Benefits Planning, Assistance, and Outreach Programs: Tips for Coordinators and Managers [PDF]

open access: yes, 2003
This publication is a human resources guide to staffing and managing effective benefits planning, assistance and outreach programs. Specifically the publication provides helpful tips and strategies for staff recruitment; interviewing; developing ...
Ridgely, Mary, Smith, Barb
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Technical writing [PDF]

open access: yesNew Zealand Journal of Geology and Geophysics, 1965
Pete Clecak, Richard W. Smith
openaire   +2 more sources

Entre Journal de voyage et Annales des Mines (1750-1850) : la constitution d'un discours technique

open access: yes, 2006
Intervention faite dans le cadre du colloque international "Du mode de production des énoncés techniques", Romain Laufer, Armand Hatchuel dir., Collège international de philosophie, décembre 2001To elaborate, to produce a technical writing means ...
Garçon, Anne-Françoise
core   +1 more source

Home - About - Disclaimer - Privacy