Results 71 to 80 of about 688,281 (304)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Staffing and Managing Benefits Planning, Assistance, and Outreach Programs: Tips for Coordinators and Managers [PDF]
, 2003 This publication is a human resources guide to staffing and managing effective benefits planning, assistance and outreach programs. Specifically the publication provides helpful tips and strategies for staff recruitment; interviewing; developing ...
Ridgely, Mary, Smith, Barb
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Report Writing (or a few useful things about writing) [PDF]
, 2009 Lecture Slides on the topic of report writing which incorporate a few in class activities.
White, Su
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Entre Journal de voyage et Annales des Mines (1750-1850) : la constitution d'un discours technique
, 2006 Intervention faite dans le cadre du colloque international "Du mode de production des énoncés techniques", Romain Laufer, Armand Hatchuel dir., Collège international de philosophie, décembre 2001To elaborate, to produce a technical writing means ...
Garçon, Anne-Françoise
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
New Zealand Journal of Geology and Geophysics, 1965 Pete Clecak, Richard W. Smith
openaire +2 more sources
Reinventing the Library at Eastern Washington University: An Intensive Strategic Planning Experience with Faculty [PDF]
, 2009 In the spring of 2006, Eastern Washington University Libraries received an institutional strategic planning grant to hold a two-week strategic planning institute with faculty members representing the six colleges at Eastern Washington University (EWU ...
Miller, Julie
core +1 more source