Results 51 to 60 of about 688,281 (304)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Teaching audience analysis to the technical student [PDF]

open access: yes
Teaching audience analysis, as practiced in a technical writing course for engineering students, is discussed. Audience analysis is described as the task of defining the audience for a particular piece of writing and determining those characteristics of ...
Brillhart, L. V., Debs, M. B.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The composing process in technical communications [PDF]

open access: yes
The theoretical construct under which technical writing exercises operate and results from a survey distributed to a random sample of teachers of technical writing are described.
Hertz, V. L.
core   +1 more source

Проблемы обучения письму детей, пишущих левой рукой [PDF]

open access: yes, 2010
У статті висвітлені проблеми навчання письма учнів, які пишуть лівою рукою. Представлені способи формування графічних і технічних навичок письма у таких дітей.The article highlights the problem of teaching writing students who write with his left hand .
Прищепа, О.Ю.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Whys and hows of in-house writing [PDF]

open access: yes
The combining of requisite technical knowledge with requisite writing ability is addressed. Considerations in the development of in-house writing courses, in-plant training, are presented and evaluated.
Lane, J. C.
core   +1 more source

Explication, compréhension et causalité dans le discours des sciences et des techniques et dans la vulgarisation scientifique [PDF]

open access: yes, 1996
Cet article propose une description de l’utilisation des marqueurs de la relation de causalité (RC) dans des textes de la collection Que sais-je? L’examen de la RC dans une perspective textuelle permet d’établir l’interrelation entre l’expression de la ...
Gagnon, Sylvie
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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