Results 81 to 90 of about 688,281 (304)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Electronic Conferencing—Its Form, Function and Potential for Technical Writing Instruction
Discourse and Writing/Rédactologie, 1989 Chelva Kanaganayakam
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Implementing a Technical Writing Program: The Algonquin Experience
Discourse and Writing/Rédactologie, 1984 Barry Barclay
doaj +1 more source
Глобалізація економіки та освітній стандарт [PDF]
, 2012 (UA) Статтю присвячено аналізу тих екстралінгвальних чинників, які передували створенню індустрії лінгвістичних та перекладацьких послуг, зумовили створення нових спеціальностей "Технічний переклад" і "Локалізація програмних продуктів" та визначають ...
Міщенко, Алла Леонідівна
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Developing a Technical Writing Programme
Discourse and Writing/Rédactologie, 1985 Reynolds Kanary
doaj +1 more source
A review of literature on communication skills development (CSD) in the engineering curriculum [PDF]
, 2008 Engineering education has expanded recently to include emphasis on the development of some very specific non-technical attributes that match a strong technical base to produce well-rounded engineering graduates who are flexible and adaptable to suit the ...
Awang, Zubaidah, Othman, Rohani
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