Results 81 to 90 of about 4,771,901 (306)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Feisty and childless (a cut and paste; a polylogue)
, 2012 This text results from a research project that analyzed publications about voluntary childlessness, a subject addressed in only a few sociological and psychological texts and almost entirely absent from poetry and fiction.
Smith, Hazel (R11761)
core
, 2018 This paper describes developmental writing paths within a Colombian major in Industrial Engineering. The accounts were created through retrospective descriptions of students' writing experiences collected by a qualitative survey and analyzing writing ...
Narvaez Cardona, Elizabeth
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Creating participatory writing cultures in UK higher education
, 2011 One particularly difficult area for higher education students is writing appropriately for their respective disciplines. As writing is a social, cultural and dialogic act, writing support should create learning events that will allow for useful social ...
Hardy, Christine +3 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Expository Writing: Analyzing Mass Media
, 2023 This course focuses on developing and refining the skills that will you need to express your voice more effectively as an academic writer. As a focus for our writing this semester, this course explores what it means to live in the age of mass media.
Walsh, Andrea
core
Electronic Conferencing—Its Form, Function and Potential for Technical Writing Instruction
Discourse and Writing/Rédactologie, 1989 Chelva Kanaganayakam
doaj +1 more source