Results 81 to 90 of about 3,891,508 (332)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Sinkless: A Preliminary Study of Stress Propagation in Group Project Social Networks using a Variant of the Abelian Sandpile Model [PDF]
, 2013 We perform social network analysis on 53 students split over three semesters and 13 groups, using conventional measures like eigenvector centrality, betweeness centrality, and degree centrality, as well as defining a variant of the Abelian Sandpile Model
Knowles, Bryan, Yang, Rong
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Engineering at San Jose State University, Summer 2008 [PDF]
, 2007 https://scholarworks.sjsu.edu/engr_news/1006/thumbnail ...
San Jose State University, Charles W. Davidson College of Engineering
core +2 more sources
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
ELEC6021 Research Methods: Report Writing [PDF]
, 2013 Slides and Handouts for this part of the ...
White, Su
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Scholars Forum: A New Model For Scholarly Communication [PDF]
, 1999 Scholarly journals have flourished for over 300 years because they successfully address a broad range of authors' needs: to communicate findings to colleagues, to establish precedence of their work, to gain validation through peer review, to establish ...
Buck, Anne M. +2 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Reinventing the Library at Eastern Washington University: An Intensive Strategic Planning Experience with Faculty [PDF]
, 2009 In the spring of 2006, Eastern Washington University Libraries received an institutional strategic planning grant to hold a two-week strategic planning institute with faculty members representing the six colleges at Eastern Washington University (EWU ...
Miller, Julie
core +1 more source