Results 61 to 70 of about 606,110 (262)
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
The Level Efficiency of Health Spending in East Java Province
JEJAK: Jurnal Ekonomi dan Kebijakan, 2019 This study aims to determine and analyze the level of technical cost efficiency, technical systems and improvement strategies that need to be done for inefficient areas in 30 districts / cities in East Java Province.
Eli Masfufah, Yozi Aulia Rahman
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Assessment of the efficiency of palm plantations using a stochastic frontier approach
Agricultural and Resource EconomicsPurpose. The purpose of this study is to (1) estimate the effect of inputs use on production with the stochastic frontier production function model approach; (2) assess the potential for increasing productivity through the study of technical, allocative ...
Saidin Nainggolan, Yanuar Fitri
doaj +1 more source
Technical efficiency in Brazilian citrus production
Bio-based and Applied Economics, 2015 The purpose of this study was to analyze the technical efficiency of citrus producing properties in Sao Paulo state, in 2009 and 2010. For this, producers were interviewed; non–parametric data envelopment analysis approach was applied to calculate ...
Felippe Clemente +2 more
doaj +1 more source
Technical efficiency in the Chilean agribusiness sector [PDF]
, 2011 The reform-process towards a higher world-market orientation has a long tradition in Chile, with all its strengths and weaknesses. The food processing industry is highly competitive on the worldmarket. The following paper investigates the technical efficiency of the Chilean food processing industry between 2001 and 2007.
Rivera Aedo, Edinson +2 more
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The weighted Russell measure of technical efficiency
European Journal of Operational Research, 1998 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
John Ruggiero, Stuart Bretschneider
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source