Results 91 to 100 of about 1,197,354 (304)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

PROGRESS IN DIGITAL IMAGE PROCESSING, 1969

open access: yes, 1970
QC 351 A7 no. 50The results of the first complete tests of the Optical Sciences Center digital image processing facility are reported. The instrumentation for digitizing film transparencies is operating well enough to provide suitable in- puts to the ...
Frieden, B. Roy   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

MULTIBAND CAMERA MONOGRAPH

open access: yes, 1969
QC 351 A7 no. 44The primary intent of this monograph is to furnish the multiband experimentalist with a convenient source of current information on aerial photo- graphic films, spectral filters, and optical -mechanical tolerances for multiband cameras ...
Slater, P. N.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A Symposium on Support and Testing of Large Astronomical Mirrors

open access: yes, 1966
QC 351 A7 no. 30This symposium was co- sponsored by the Kitt Peak National Observatory (Dr. D. L. Crawford) and the Optical Sciences Center and Steward Observatory of the University of Arizona (Dr. A. B. Meinel). The idea grew from the recognition of the
Stockton, Martha W.   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

UMPSA and Aschaffenburg University of Applied Sciences strengthen ties to boost Technical Education and WBL Initiatives [PDF]

open access: yes
ASCHAFFENBURG, GERMANY, 22 May 2024 - The Malaysia Technical University Network (MTUN) Advanced TVET delegation, accompanied by the Ministry of Higher Education, continued their first-day work visit to Aschaffenburg University of Applied Sciences (UAS)
Nur Ezzati, Mohd Nasir
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

PHOTOGRAPHIC GRAIN NOISE SUPPRESSION BY DENSITY QUANTIZATION: ITS INFLUENCE ON IMAGE QUALITY

open access: yes, 1975
QC 351 A7 no. 85A technique is described for suppressing unwanted grain noise in scanned and digitized photographic images. The technique employs the rms granularity statistics of the film to divide, or quantize, the density range of the digital image ...
Hoffman, Robert Stocking, 1944-
core  

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