Results 101 to 110 of about 15,653,086 (211)
PROGRESS IN ANALOG IMAGE PROCESSING
, 1968 QC 351 A7 no. 33Image formation is a major area of Optical Sciences Center research. Parallel studies are progressing on analog and digital image processing techniques. This report describes the current progress in the analog apparatus and research.
Thunen, John G., Burke, James J.
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
MULTIPLE SOURCE TESTING OF CAMERA SYSTEMS
, 1970 QC 351 A7 no. 54It is possible to use a target of two coherent point sources, with a separation much greater than the resolution limit of a diffraction -limited lens, to determine the best focus of a photographic system.
Rodriguez-Torres, Cristobal
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
OPTIMIZATION AND EVALUATION OF MANUFACTURING TOLERANCES OF A THREE-MIRROR ASPHERIC CAMERA
, 1971 QC 351 A7 no. 61In an attempt to design a three -mirror aspheric camera, a procedure was developed to arrive at a design with a minimum obscuration ratio.
Van Workum, John A.
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
FURTHER STUDIES OF THE DETECTABILITY OF DEGRADED VISUAL SIGNALS
, 1973 QC 351 A7 no. 78Observers responded to abstract forms (quadrigons) in six experiments, under a signal detection paradigm. Duration of stimulus exposure was shown to have strong effects upon detection accuracy (two studies); immediate feedback of accuracy
Wheeler, Lawrence
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
EARTH-ORBITAL ELECTRO-OPTICAL MULTIBAND CAMERA
, 1970 QC 351 A7 no. 62Multiband photography has been used for several years as a tool for aerial reconnaissance. Recent experiments indicate a potential value in earth resources studies, particularly those utilizing an electro-optical image sensor. This report
Baker, L. Ralph
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source