Results 51 to 60 of about 6,695,348 (295)

Primary Results of the SALAMANDER Registry: A Multicenter Observational Cohort Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The balance between thromboembolic complications and bleeding risk in anticoagulated patients with atrial fibrillation remains challenging, with left atrial appendage occlusion (LAAO) representing a potential alternative.
Wojciech Wańha   +59 more
doaj   +1 more source

Virtual Treatment Zone From Cone Beam CT Commonly Alters Treatment Plan and Identifies Tumor at Risk for Under-Treatment in US or US Fusion-Guided Microwave Ablation of Liver Tumors

open access: yesTechnology in Cancer Research & Treatment, 2023
Tumor ablation is included in several major cancer therapy guidelines. One technical challenge of percutaneous ablation is targeting and verification of complete treatment, which is prone to operator variabilities and human imperfections and are directly
Antonio Arrichiello MD   +11 more
doaj   +1 more source

Therapeutic vaccines for chronic diseases: successes and technical challenges [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2011
Abstract Chronic, non-communicable diseases are the major cause of death and disability worldwide and have replaced infectious diseases as the major burden of society in large parts of the world. Despite the complexity of chronic diseases, relatively few predisposing risk factors have been identified by the World Health Organization ...
Bachmann, M, Jennings, G
openaire   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Hepatic Vein–Inferior Vena Cava Confluence Angle as a Key Anatomical Predictor of Technical Success in Transjugular Liver Biopsy

open access: yesLivers
Background/Objectives: Transjugular liver biopsy (TJLB) occasionally fails, most commonly because of difficulty in hepatic vein (HV) catheterization. We investigated whether the HV–inferior vena cava (IVC) confluence angle measured on CT or MRI could ...
Naohiro Wada   +6 more
doaj   +1 more source

Carbon Free Boston: Transportation Technical Report [PDF]

open access: yes, 2019
Part of a series of reports that includes: Carbon Free Boston: Summary Report; Carbon Free Boston: Social Equity Report; Carbon Free Boston: Technical Summary; Carbon Free Boston: Buildings Technical Report; Carbon Free Boston: Waste Technical ...
Cleveland, Cutler J.   +6 more
core  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Success for all: Improving Maori and Pasifika student success in degree-level studies

open access: yes, 2010
The Success for All project sought to examine the ways in which nonlecture teaching helps or hinders Māori student and Pasifika student success in preparing for or completing degree-level studies. Good practice was to be identified.
Brown, Deidre   +14 more
core   +1 more source

Central Carolina Technical College 2022 Fact Book

open access: yes, 2022
Central Carolina Technical College annually publishes a fact book with general information about the college; enrollment and demographic information; academic program profile information; retention, transfer, graduation and success rates; and cohort and ...
Central Carolina Technical College, Research and Institutional Effectiveness
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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