Results 41 to 50 of about 4,459,271 (298)

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Evaluation Criteria and Surgical Technique for Transoral Access to the Thyroid Gland: Experimental Study

open access: yesJournal of Investigative Surgery, 2019
Background: The development of endoscopic techniques motivated surgeons to search for alternative and more cosmetic approaches for thyroid and parathyroid surgery.
Alexander M. Shulutko   +7 more
doaj   +1 more source

Principles and Techniques for Competence Formation in Russian Dialogical Speech among Iraqi University of Baghdad Students

open access: yesPolylinguality and Transcultural Practices, 2020
The article has an attempt to name the principles and techniques for competence formation in Russian dialogical speech among Iraqi University of Baghdad students.
Munder Mulla Kadhim, Hisham Ali Hisham
doaj   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Techniques and tools used in trauma patients transfer: a review

open access: yesSaudi Journal of Emergency Medicine, 2021
Secondary spinal cord injury is a major concern for trauma patients. Thereby, proposing the necessity for the development and application of spinal immobilization techniques to guarantee minimal motion during transfer of the patients from the trauma ...
Albraa F. Shodari   +4 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

The Impact of Digital Fabrication in Architecture [PDF]

open access: yesEngineering and Technology Journal, 2016
The development of the digital technology has led to expand the design Capabilities of architects, especially in the field of generating curved forms with formal complexity which was unattainable with the traditional methods of construction, thus ...
Ali Muhsen Jaafer Al-khafaji   +1 more
doaj   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

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