Safety evaluation of an extension of use of the food enzyme glucan 1,4-α-maltohydrolase from the genetically modified <i>Bacillus licheniformis</i> strain NZYM-FR. [PDF]
EFSA Panel on Food Enzymes (FEZ) +15 more
europepmc +1 more source
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of l-histidine monohydrochloride monohydrate produced with <i>Escherichia coli</i>CCTCC M 20241089 for all animal species (Anhui Huaheng Biotechnology Co., Ltd). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +19 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Dispersion of Graphene Oxide: Evaluating Ionic Surfactants for Nanocomposite Cement Applications. [PDF]
Baral S, Raghavendra R, Thomas K, Das R.
europepmc +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Effect of Oenological Additives on Oral Aroma Retention During Wine Tasting. [PDF]
Velázquez-Martínez RI +3 more
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Biosurfactants in Food: Advances, Innovative Applications and Functional Perspectives. [PDF]
Silva RRD +6 more
europepmc +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source

