Assessment of the feed additive consisting of bentonite (dioctahedral montmorillonite) as an anticaking agent for all animal species and as a substance for reduction of the contamination of feed by mycotoxins for pigs, poultry and ruminants for the renewal of its authorisation (BASF SE). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +24 more
europepmc +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Safety evaluation of an extension of use of the food enzyme chymotrypsin from the genetically modified <i>Bacillus licheniformis</i> strain NZYM-RH. [PDF]
EFSA Panel on Food Enzymes (FEZ) +15 more
europepmc +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Edible coatings and films in meat preservation: Materials, functional mechanisms, and technological challenges. [PDF]
Pratama BP +13 more
europepmc +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Safety evaluation of an extension of use of the food enzyme bacillolysin from the non-genetically modified <i>Bacillus amyloliquefaciens</i> strain HPN 131. [PDF]
EFSA Panel on Food Enzymes (FEZ) +15 more
europepmc +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Comparative Analysis of Food Additives in Products with and Without Added Sugar on the Polish Market. [PDF]
Kołodziejczyk A, Nowak J.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source

