Results 61 to 70 of about 2,049,634 (287)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Plastics in biota: technological readiness level of current methodologies

Microplastics and Nanoplastics
Plastics are persistent in the environment and may be ingested by organisms where they may cause physical harm or release plastic additives. Monitoring is a crucial mechanism to assess the risk of plastics to the marine and terrestrial ecosystem ...
David Vanavermaete, A. Lusher, Jakob Strand, Esteban Abad, M. Farré, Emilie Kallenbach, Michael Dekimpe, K. Verlé, Sebastian Primpke, Stefano Aliani, Bavo De Witte   +10 more
semanticscholar   +1 more source

Chia (Salvia hispanica L.) seed mucilage as a fat replacer in yogurts: Effect on their nutritional, technological, and sensory properties.

Journal of Dairy Science, 2020
Growing consumer demand for healthy and nutritious products has motivated scientists and food manufacturers to design novel dairy products with higher fiber levels and lower fat content that are free of chemical additives.
Susana Ribes, N. Pena, A. Fuentes, P. Talens, J. Barat   +4 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Safety and efficacy of a feed additive consisting of Lacticaseibacillus huelsenbergensis DSM 115424 for all animal species (Lactosan GmbH & Co. KG)

EFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on Lacticaseibacillus huelsenbergensis DSM 115424 when used as a technological additive to improve ensiling of all fresh plant material for all animal ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Montserrat Anguita, Matteo L. Innocenti, Yolanda García‐Cazorla   +19 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Safety of a feed additive consisting of xanthan gum (produced with Xanthomonas campestris strains ATCC SD‐7012, DSM 23730, CNCM I‐4861 and CIP 74.23) for all animal species with the exception of cats and aquatic species (BIOPOLYMER International)

EFSA Journal
Following a request from the European Commission, the European Food Safety Authority was asked to deliver a scientific opinion on the safety of xanthan gum as a technological feed additive for all animal species, with the exception of cats and aquatic ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Montserrat Anguita, Nicole Bozzi Cionci, Rosella Brozzi, Jaume Galobart, Matteo L. Innocenti, Fabiola Pizzo, Maria Vittoria Vettori, Angelica Amaduzzi   +24 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Assessment of the feed additive consisting of Lactiplantibacillus plantarum DSM 16627 for all animal species for the renewal of its authorisation (Microferm Ltd.)

EFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of the authorisation of a preparation Lactiplantibacillus plantarum DSM 16627 as a technological additive to
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Montserrat Anguita, Nicole Bozzi Cionci, Matteo L. Innocenti, Joana Revez   +20 more
doaj   +1 more source

Critical review of the safety assessment of titanium dioxide additives in food

Journal of Nanobiotechnology, 2018
Nanomaterial engineering provides an important technological advance that offers substantial benefits for applications not only in the production and processing, but also in the packaging and storage of food.
H. Winkler, T. Notter, U. Meyer, H. Naegeli   +3 more
semanticscholar   +1 more source