Results 111 to 120 of about 668,692 (311)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

How does environmental tax reform drive corporate innovation to green technologies? Quasi-natural experimental evidence from China

Journal of Business Economics and Management
How to motivate enterprises to formulate green technology (GT) innovation is crucial for promoting green development and minimizing pollution control costs.
Hui Hu, Yuqi Zhu, Lin Ye, Yulong Wang
doaj   +1 more source

EFFECTS OF TILLAGE TECHNOLOGY ON ENERGETIC EFFICIENCY OF RAPESEED PLANTATION FOR BIOFUEL PRODUCTION [PDF]

Applied Computer Science, 2014
Biofuel production, as well as any other production processes, involves a number of conversion steps each of those is connected with unavoidable consumption of energy.
Olga ORYNYCZ, Andrzej WASIAK
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Evolutionary Game of Multiple Subjects Collaborative Innovation Under Double Uncertainty

Complexity
Multisubject technology collaborative innovation serves as an essential driving force to improve technology transfer efficiency as well as implement the innovation-driven strategy.
Xumei Yuan, Ming Zhang, Fuli Wei, Xu Zhang   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Research on the impact of environmental regulations on green technological innovation in China from the perspective of digital transformation: a threshold model approach

Environmental Research Communications
The digital transformation in developing countries is crucial in determining whether environmental regulations can better facilitate green technological innovation.
Yanfei Xiao, Baoli Zhang, Huilin Wang
doaj   +1 more source

Pour une approche esthétique, technologique et procédurale de la fabrication des atmosphères : étude de Roma d’Alfonso Cuarón

Ambiances
In Roma, Alfonso Cuarón builds a world with a very singular atmosphere, at once a meticulous, documented reconstruction of the 1970s Mexico City and an intimate, detailed re-creation of memory.
Isabelle Singer
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Strategic perspectives on modularity [PDF]

In this paper we argue that the debate on modularity has come to a point where a consensus is slowly emerging. However, we also contend that this consensus is clearly technology driven. In particular, no room is left for firm strategies.
Florent Catel, Jean-Charles Monateri
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