Results 121 to 130 of about 668,692 (311)
The Specter of Pervasiveness: Pacifica, New Media, and Freedom of Speech [PDF]
, 1998 Under the legal doctrine of pervasiveness, media such as television and radio get much less protection from censorship than do print media. The Supreme Court should reject the pervasiveness doctrine as a dangerously broad and vague excuse for speech ...
Jonathan D. Wallace
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Trends and Challenges in Pathology Practice : Choices and necessities
Sultan Qaboos University Medical Journal, 2011 The way we provide healthcare is influenced by ongoing experiences, increased knowledge, new discoveries and scientific as well as technological advances.
Hassan MH Kamel
doaj
A novel hybrid architecture for agriculture and land use in an integrated modeling framework : MATISSE (Methods and Tools for Integrated Sustainability Assesment) [PDF]
, 2008 As part of a cluster workshop on sustainability of hydrogen transport technologies held in Frankfurt on 21st February 2006, MATISSE researchers conducted break-out discussion groups with, and distributed self-completion questionnaires to, stakeholders in
Cassen, Christophe +4 more
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Nine Regimes of Radio Spectrum Management: A 4-Step Decision Guide [PDF]
Diverse radio spectrum management regimes are defined according to 4 levels of options: - Should frequencies be allocated according to a harmonised plan? - Should the technologies allowed be standardised?
Gérard Pogorel
core
Bullion production in imperial China and its significance for sulphide ore smelting world-wide [PDF]
, 2015 Gold and silver production was of major importance for almost all ancient societies but has been rarely studied archaeologically. Here we present a reconstruction of a previously undocumented technology used to recover gold, silver and lead at the site ...
Chen, J +6 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source