Results 141 to 150 of about 668,692 (311)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
An overview of psychological factors in mobility choices: the impact on pro-environmental behavior
Discover SustainabilityDespite the current increased spread of modern mobility options in urban areas aimed at inducing changes in mobility choices, their integration into daily life remains sporadic, reducing their potential impact on the adoption of shared mobility services ...
Marilina Pellegrini +1 more
doaj +1 more source
Technology adoption and factor proportions in open economies : theory and evidence from the global computer industry [PDF]
Theories of international trade assume that all countries use similar and exogenous technologies in the production of any good. This paper relaxes this assumption. The marriage of literatures on biased technical change and trade yields a tractable theory,
Cusolito , Ana P., Lederman, Daniel
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Managing ambiguity of strategic alliances – the role of negotiations [PDF]
Strategic alliances have become an important part of most company's portfolios. In an era of rapid technological change, the ever rapidly changing competitive landscape, and the globalization of competition more and more companies are choosing to ...
Luminiþa Vochiþa
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Space, growth and technology: an integrated dynamic approach [PDF]
Economic phenomena are interrelated. From a growth perspective, time analysis concerning the choices of present and future consumption and the choices between the allocation of scientific resources should be combined with a space analysis regarding the ...
Gomes, Orlando
core +4 more sources
Technology, Information and the Decentralization of the Firm [PDF]
This paper develops a framework to analyze the relationship between the diffusion of new technologies and the decentralization decisions of firms. Centralized control relies on the information of the principal, which we equate with publicly available ...
Claire Lelarge +4 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Cadernos do LEPAARQ, 2012 O estilo tecnológico é o resultado de escolhas culturalmente determinadas que se refletem na seleção das matérias primas, nas técnicas e seqüências de produção e nos resultados materiais destas escolhas. A comparação de estilos tecnológicos de diferentes
Adriana Schmidt Dias
doaj