Results 101 to 110 of about 668,692 (311)
Collaboration and the Net generation: The changing characteristics of first year university students [PDF]
, 2009 This paper reports on the first phase of research that investigates the Net generation entering university. The paper focuses on claims about the Net generation’s relationship to collaboration and cooperation and the ways that this relationship is ...
Jones, Chris, Ramanau, Ruslan
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Optimal psycholinguistic environments for distance foreign langauge learning [PDF]
, 2001 Rational choices among the numerous technological options available for foreign language teaching need to be based, in part, on psycholinguistic considerations. Which technological advances help create an optimal psycholinguistic environment for language
Doughty, Catherine J., Long, Michael H.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Technology and development: Unpacking the relationship(s) [PDF]
Innovation is, as Joseph Schumpeter once pointed out, above all a combinatory phenomenon. Success in accessing knowledge and exploiting it in a way that is beneficial for development depends on the ability to combine many different skills and resources ...
Jan Fagerberg, Martin Srholec
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A Second-Order Approximation to Technology Choices [PDF]
Resources used in scientific activities are, as any other, scarce. Hence, the economic system has, in every time moment, to choose how to allocate technological inputs.
Orlando Gomes
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Dynamic implications of patenting for crop genetic resources: [PDF]
In a climate of rapid technological change, it is important to evaluate policies on the innovation incentives that result from the introduction of intellectual property rights as they relate to agricultural genetic resources.
Koo, Bonwoo, Wright, Brian D.
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Ceramic composition at Chalcolithic Shiqmim, northern Negev desert, Israel: investigating technology and provenance using thin section petrography, instrumental geochemistry and calcareous nannofossils [PDF]
, 2018 Technological innovations in ceramic production and other crafts are hallmarks of the Chalcolithic period (4500–3600 BCE) in the southern Levant, but details of manufacturing traditions have not been fully investigated using the range of analytical ...
Burton, Margie M +3 more
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