Results 31 to 40 of about 40,350 (266)

Government Patenting and Technology Transfer [PDF]

SSRN Electronic Journal, 2006
Intellectual property rights such as patents protect new inventions from imitation and competition. Patents' major objective is to provide incentives for invention, sacrificing short-term market efficiency for long-term economic gains. Although patents are primarily granted to private firms, policy changes over the last 25 years have resulted in ...
Heisey, Paul W., Day-Rubenstein, Kelly A., King, John L.   +2 more
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Digital Twin Empowering Whole-Lifecycle Governance of Urban Infrastructure: A Review of Technological Embedding, Organizational Change, and Institutional Reconstruction

Buildings
As a frontier direction of engineering informatics, Digital Twin technology offers new technical possibilities for the whole-lifecycle governance of urban infrastructure.
Xiansheng Chen, Sha Liu, Yang Zhao, Changxu Zheng, Yaping Zhang   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Impact of governance and technological progress on internet banking adoption across two major 21st century crises

Cogent Business & Management
This study explores the relationship between governance, technological progress, and internet banking adoption in the European Union (EU) from 2000 to 2023, focusing on the global financial crisis of 2008 and the COVID-19 pandemic.
Iulia Cristina Iuga
doaj   +1 more source

The Governance of Information and Communication Technology

Australasian Journal of Information Systems, 2009
Information and communication technologies (ICT) are ubiquitous but governance in the industry is piecemeal at best. Government regulations and various standards apply to parts of the industry, and professional bodies, the Australian Computer Society (ACS) for example, have some influence on individuals, on professional education and on policies.
John Weckert, Richard Lucas
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Corporate governance, technological innovation, and corporate performance: Evidence from China

Heliyon
Corporate governance plays an important role in achieving high-quality economic development and sustainable corporate development. In recent years, as listed companies face increasing challenges in social responsibility issues such as environmental ...
Yinlong Ma, Nur Syafiqah Binti A. Rahim, Siti Aisyah Bt Panatik, Ruirui Li   +3 more
doaj   +1 more source