Results 41 to 50 of about 526,015 (308)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Addressing energy poverty through technological and governance innovation

Energy, Sustainability and Society, 2022
Background Energy poverty has gained much traction over the last decades, holding both high multidisciplinary conceptual value, but also profound implications from a social policy perspective, being closely linked to the quality of life and well-being ...
Anais Varo, George Jiglau, Katrin Grossmann, Rachel Guyet   +3 more
doaj   +1 more source

Governing Networks and Rule-Making in Cyberspace [PDF]

, 1996
The global network environment defies traditional regulatory theories and policymaking practices. At present, policymakers and private sector organizations are searching for appropriate regulatory strategies to encourage and channel the global ...
Reidenberg, Joel R.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Corporate governance, technological innovation, and corporate performance: Evidence from China

Heliyon
Corporate governance plays an important role in achieving high-quality economic development and sustainable corporate development. In recent years, as listed companies face increasing challenges in social responsibility issues such as environmental ...
Yinlong Ma, Nur Syafiqah Binti A. Rahim, Siti Aisyah Bt Panatik, Ruirui Li   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Planning in a technological society: discussing the London Plan [PDF]

, 2010
The sustainable development agenda has influenced the focus of urban planning policy in many countries and localities; this article argues that its influence has been much more widespread, affecting not just the content of planning but also its ...
Rydin, Y
core  

Economic growth, innovation systems, and institutional change: a trilogy in five parts [PDF]

, 2005
Development and growth are products of the interplay and interaction among heterogeneous actors operating in specific institutional settings. There is a much alluded-to, but under-investigated, link between economic growth, innovation systems, and ...
Arora, Saurabh, Ciarli, Tommaso, Parto, Saeed   +2 more
core   +4 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Policy Performance and Governance Capacities in the OECD and EU. Sustainable Governance Indicators 2018. Bertelsmann Studies [PDF]

, 2014
This year marks the release of the third edition of the Sustainable Governance Indicators (SGI). The highly developed industrial nations continue to face enormous challenges, due not only to aftereffects of the global economic and financial crisis and ...
Azahaf, Najim, Schraad-Tischler, Daniel
core