Results 31 to 40 of about 81,391 (264)

Technological innovations in soccer

open access: yesRevista de Ciência e Inovação do IF Farroupilha
Although Brazilian soccer is undergoing intense digitalization, there is still little evidence of the real impact of these innovations on value creation for clubs and fans.
Thiago Delpino Petrocchi   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cellular and Systemic Toxicity Induced by Sunscreen and Paraben Mixtures and the Implications for Root Development in Cultivated Plants

open access: yesJournal of Toxicology
Sunscreens and parabens contaminate agricultural areas worldwide; however, the effects of these micropollutants in mixture on cultivated plants have not yet been reported. This study evaluated the cellular and systemic toxicity induced by octocrylene (OC)
Ana Elisa Maehashi   +12 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Information Technology Innovation [PDF]

open access: yesThe Permanente Journal, 2008
“Innovation is what distinguishes between a leader and a follower” is a statement often attributed to Apple cofounder Steve Jobs. Nowhere is this saying truer than in the realm of information technology (IT), where the blistering pace of change can make even casual observers dizzy. Yet IT innovation can be a two-edged sword.
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The importance of innovation in the Czech and Slovak spa industry: the COVID-19 era and beyond

open access: yesSport i Turystyka
This study aims to analyze the scope, structure, and perceived benefits of innovations implemented by spa businesses in the Czech Republic and the Slovak Republic over a period spanning the pre-COVID-19, pandemic, and post-pandemic phases (2018–2022 ...
Josef Pátek   +3 more
doaj   +1 more source

Process Innovations as the Value of Trade and Technological Processes

open access: yesСовременная конкуренция, 2022
Relevance of the research topic. In retail, there is an active introduction of innovations in all segments, in the struggle for survival and efficiency improvement; trading enterprises are actively searching for innovative technologies, primarily IT ...
Galina N. Chernukhina
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Technological Innovations to Address Health Challenges [PDF]

open access: yesZhongguo quanke yixue
The accelerations of globalization, climate change, and population aging gradually increase the complex challenges to human health. Globalization-induced global health issues significantly increase the speed and range of infectious disease transmission ...
LIU Jue, LIANG Wannian
doaj   +1 more source

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