Results 111 to 120 of about 20,169,449 (332)

Spillovers in product and process innovation: evidence from manufacturing firms. [PDF]

open access: yes
This paper proposes a new empirical approach to assess the impact of knowledge spillovers on firms' productivity and demand. I consider a model where process innovations spillovers to other firms raise firms relative efficiency and technological ...
Ornaghi, Carmine
core  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

The Machine Starts: Computers as Collaborators in Writing [PDF]

open access: yes, 2011
The penetration of digital technologies into the process of creating and disseminating narratives is no longer a new phenomenon, but perhaps what does still seem strange and far-fetched is the suggestion that machines are collaborators and authors in ...
Flintham, Joe
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

The location of the Spanish technological centers [PDF]

open access: yes
The Technological Centers have been created with the aim of being a supplier of different R&D's activities and services for those entreprises with a lack of material and financial resources to develop by themselves an innovation process.
Fuster Olivares, Antonio   +2 more
core  

Study of the lateral pass width for conventional and ultrasonic vibrations-assisted ball burnishing on Ti-6Al-4V specimens [PDF]

open access: yes, 2016
Ball burnishing is a technological finishing process based on plastic deformation of the objective surface by means of a hard ball gliding over it. Along with its easiness of application, possible on the same machine where machining was performed [1 ...
Gómez Gras, Giovanni   +3 more
core  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

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